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Efecto de la exposiciòn a CdCl2 sobre la metilación y expresión de los genes SOD-2 y GPx-1 en la línea celular HepG2
(Universidad Autónoma de Guerrero (México), 2017-07)
Introduction: Cadmium (Cd) is a highly toxic and carcinogenic metal. The mechanisms by which it exerts its toxic effects are not fully elucidated; especially the epigenetic role. Cd modulates methylation patterns and alters ...
Actividad antibacteriana y antiinflamatoria de extractos y fracciones de Agave cupreata
(Universidad Autónoma de Guerrero (México), 2017-04)
Objetive: The aim of this study was to evaluate the antibacterial and anti-inflammatory activities of extracts and fractions obtained from Agave cupreata leaves.
Caracterización fitoquímica y actividad antiproliferativa de extractos de hoja de Ficus crocata en la línea celular MDA-MB-231
(Universidad Autónoma de Guerrero (México), 2018-06)
Background: The Ficus genus comprises approximately 750 species of Moraceae family. Recent studies have been demonstrated that some species of this genus showed pharmacological activities, including antitumor activity. ...
Polimorfismos t786c, g894t y g10t en el gen NOS3 y su relación con presión arterial alta en población guerrerense
(Universidad Autónoma de Guerrero (México), 2017-01)
Globally, one in three adults has high blood pressure. Nitric oxide (NO) is an endogenous free radical, involved in vasorelaxation, and therefore, in reducing vascular resistance and blood pressure. Nitric oxide is synthesized ...
Polimorfismos en el gen PON1 y daño al DNA en población expuesta ocupacionalmente a plaguicidas organofosforados
(Universidad Autónoma de Guerrero (México), 2014-06)
PON1 is an enzyme that hydrolyzes the active metabolites of OP (oxons). It has determined that single nucleotide polymorphisms (SNP) in the promoter (108CT) and coding (L55M and Q192R) region of PON1 gene induce variations ...
Efecto de la leptina recombinante sobre la producción de citocinas proinflamatorias (il-1, il-6 y tnf) en células mononucleares de sangre periférica con variantes polimórficas en el gen LEPR
(Universidad Autónoma de Guerrero (México), 2012-10)
Leptin is a hormone that regulates energy balance. In mononuclears cells promotes proinflammatory cytokine production such as IL-1, IL-6 y TNF. In the leptin receptor gene (LEPR), have been described various alterations, ...
Microbiota intestinal, su papel en la endotoxemia y en el perfil metabólico de jóvenes
(Universidad Autónoma de Guerrero (México), 2013-11)
The intestinal microbiota (MI) plays an important role in human metabolism, studies suggest that the imbalance can cause a metabolic endotoxemia impact on weight gain and insulin resistance. Analyze the association between ...
Diversidad de la región variable 3 del oncogén cagA de H. pylori en pacientes con gastritis crónica y cáncer gástrico
(Universidad Autónoma de Guerrero (México), 2013-09)
Chronic infection with Helicobacter pylori is associated with chronic gastritis, peptic ulcer and gastric cancer. Strains of H. pylori cagA-positive increases the risk of gastric pathology. The carcinogenic potential of ...
Resistencia a la insulina inducida por exposición a metamidofos: participación del estrés oxidativo
(Universidad Autónoma de Guerrero (México), 2018-01)
Insulin resistance (IR) is the incapacity observed in tissues for responding to biological activity induce by insulin stimulation; this condition has been linked with the development of several chronic diseases. The causes ...
Efecto del resveratrol sobre el nivel de expresión de los transportadores de glucosa GLUT en isquemia cerebral in vivo
(Universidad Autónoma de Guerrero (México), 2014-01)
Ischemic stroke results from occlusion of a major cerebral artery and involves a cascade of metabolic events that begin during insult and proceed well into the blood flow recovery period [reperfusion (R)]. Impairment of ...