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MMP-2 salivary activity in type 2 diabetes mellitus patients
(Diabetology & Metabolic Syndrome, 2019-01)
Type 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirec¿ tional relationship. The uncontrolled levels of glucose in T2DM patients change the pathophysiology and balance of ...
The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
(BioMed Research International, 2017-10-10)
Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
(BioMed Central, 2016-03-14)
Background: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins ...
HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
(Cellular Physiology and Biochemistry, 2019-12-05)
Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some ...
High relative abundance of firmicutes and increased TNF- ¿ levels correlate with obesity in children.
(Salud Pública de México, 2017-02-24)
To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Materials and methods. Anthropometric data were obtained from 890 children under 14 years ...
Influence of serum leptin levels and Q223R leptin receptor polymorphism on clinical characteristic of patients with rheumatoid arthritis from Western Mexico.
(eJIFCC, 2018-11)
The aim of the present study was to evaluate the possible association between the Q223R Leptin receptor (LEPR) polymorphism (A>G; rs1137101) and leptin levels in patients with rheumatoid arthritis (RA) from Western Mexico.
Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia.
(ONCOLOGY LETTERS, 2017-08-23)
Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted ...
Antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with indium and iron
(Microbiology Research International, 2016-11)
The need for new antimicrobial compounds has drawn attention on developing new and emerging materials based on nanoparticles with antimicrobial activity. The aim of this research was to evaluate the antibacterial activity ...
Phenotypic and molecular characterization of Klebsiella spp. Isolates causing community-acquired infections
(Elsevier, 2018-02)
Klebsiella spp. isolates from community-acquired infections were characterized. A total of 39 Klebsiella spp. isolates were obtained from outpatients at four rural hospitals in Mexico (2013-2014). The biochemical tests ...
Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects
(BioMed Central, 2015-09-13)
Background: Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and the relationship between diet and genes in the presence of other ...