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Papel de Src sobre marcadores clásicos de la transición epitelio-mesenquimal en células epiteliales mamarias estimuladas con leptina
(Universidad Autónoma de Guerrero (México), 2017-12)
Background: Several studies demonstrate an association between obesity and breast cancer (BC). Leptin is a hormone secreted by adipocytes which increases during obesity. Experimental evidence shown that leptin may promote ...
Efecto de la infección por Gardnerella vaginalis sobre la respuesta inmune innata en lesión escamosa intraepitelial de cérvix uterino y la línea celular HeLa
(Universidad Autónoma de Guerrero (México), 2018-11)
Bacterial vaginosis (BV) is a polymicrobial clinical entity characterized by the lack of inflammatory cells. However, in cervicovaginal fluids of women with BV, alterations in inflammatory cytokine levels have been reported ...
Polimorfismos en los genes de adiponectina (RS1501299) y de su receptor 2 (RS767870) asociados al síndrome metabólico
(Universidad Autónoma de Guerrero (México), 2012-11)
Background: Adiponectin stimulates fatty acid oxidation, reduces triglycerides, improves glucose metabolism and exerts a protective effect on blood vessels due to its effect anti-inflammatory and anti-atherogenic. Variation ...
Marcadores de disfunción endotelial asociados con riesgo cardiovascular en jóvenes con obesidad y peso normal
(Universidad Autónoma de Guerrero (México), 2013-10)
Obesity promotes endothelial dysfunction causing the detachment of endothelial cells and overexpression of cell adhesion molecules. Objective. To evaluate the ratio of the number of circulating endothelial cells and levels ...
Análisis proteómico en tejidos de cáncer epitelial de ovario de pacientes resistentes a la quimioterapia de primera línea
(Universidad Autónoma de Guerrero (México), 2013-10)
The agents of platinum and taxanes are the standard chemotherapy to treat ovarian epithelial cancer for more than 30 years, however, 70% of patients have resistance to these medications. In an effort to identify the cellular ...
Polimorfismos -511 T/C, -31 C/T y 3954 C/T de IL-1B en enfermedad periodontal en población guerrerense
(Universidad Autónoma de Guerrero (México), 2013-10)
The polymorphisms -511 T/C, -31 C/T and +3954 C/T of IL-1B gene are associated with the induction of inflammation and have been associated with the risk for developing periodontal disease. The aim of this work was to ...
Evaluación de la inmunogenicidad y efecto protector de la vacuna oral S3Pvac-papaya contra la cisticercosis en cerdos
(Universidad Autónoma de Guerrero (México), 2014-01)
Neurocysticercosis is a parasitic disease caused by the establishment of the larval stage of Taenia solium, which can be established in humans or pigs. Among the proposed control interventions include prevention of porcine ...
Efecto de las variantes comunes en los genes SLC22A1 y SLC22A2 sobre el control glicémico de pacientes con diabetes tipo 2 tratados con metformina
(Universidad Autónoma de Guerrero (México), 2019-01)
The organic cation transporters (OCT1 and OCT2) and the multidrug and toxin extrusiontransporter 1 (MATE1), encoded by the SLC22A1, SLC22A2, and SLC47A1 genes, respectively, are responsible for the absorption of the metformin ...
Daño genotóxico en linfocitos humanos expuestos in vitro a la mezcla de permetrina-aletrina
(Universidad Autónoma de Guerrero (México), 2010-03)
Pyrethroids are synthetic insecticides widely used in public health programs and in agriculture. In developing countries a mixture of the pyrethroids permethrin and allethrin is used as space spray to control the overpopulation ...
Expresión de COX-2 en entamoeba histolytica durante la interacción trofozoíto-fibronectina
(Universidad Autónoma de Guerrero (México), 2019-11)
Recently it has been demonstrated that Entamoeba histolytica synthesizes mRNA and COX-2 like protein during the production of liver abscesses in hamsters. Also, PGE2 synthesis in the trophozoites has been reported as an ...