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A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile
(International Journal of Immunopathology and Pharmacology, 2020-12-21)
The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic ...
Efecto de la disminución de HOTAIR en la hidroximetilación global en la línea celular HeLa.
(Universidad Autónoma de Guerrero (México), 2019-01)
Genetic and epigenetic alterations lead to the initiation and development of cancer. Epigenome of cancer cell is characterized by aberrant methylation of tumor suppressor genes, the functional consequence is the transcriptional ...
Transregulation of microRNA miR-21 promoter by AP-1 transcription factor in cervical cancer cells.
(Cancer Cell International, 2019-01)
Gene expression profiles have demonstrated that miR-21 expression is altered in almost all types of cancers and it has been classified as an oncogenic microRNA. Persistent HPV infection is the main etiologic agent in ...
La leptina promueve la expresión de Hic-5 y la formación de puntos de actina por la vía dependiente de FAK-Src en células epiteliales mamarias MCF10A.
(Biomédica, 2019-01-01)
Leptin is a hormone secreted by adipocytes that has been associated with the epithelial-mesenchymal transition (EMT). Additionally, leptin promotes the migration and invasion of mammary epithelial cells through the activation ...
New insights into radioresistance in breast cancer identify a dual function of miR-122 as a tumor suppressor and oncomiR.
(FebsPress, 2019-04-18)
Radioresistance of tumor cells gives rise to local recurrence and disease progression in many patients. MicroRNAs (miRNAs) are master regulators of gene expression that control oncogenic pathways to modulate the radiotherapy ...
Relationship of Excess Weight with Clinical Activity and Dietary Intake Deficiencies in Systemic Lupus Erythematosus Patients.
(2019-11-06)
Obesity and nutrients intake deficiencies may contribute to the clinical manifestations and inflammatory processes in systemic lupus erythematosus (SLE). The aim of this study was to assess the relationship between nutritional ...
Multiple infections by EBV, HCMV and Helicobacter pylori are highly frequent in patients with chronic gastritis and gastric cancer from Southwest Mexico.
(Medicine, 2019-12)
The chronic inflammation and damage to the gastric epithelium induced by Helicobacter pylori (H. pylori) are the main risk factors for gastric cancer development. Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) ...
CagL polymorphisms D58/K59 are predominant in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis.
(Gut Pathogens, 2019-02-13)
Helicobacter pylori is a Gram¿negative bacterium that colonizes the gastric mucosa in humans. One of the main virulence factors of H. pylori is the cag pathogenicity island (cagPAI), which encodes a type 4¿secretion system ...
Cervical cancer stem cell-associated genes: Prognostic implications in cervical cancer (Review).
(Oncology Letters, 2019-03-18)
Cervical cancer is the fourth most common type of gynecological malignancy to affect females, worldwide. Although high-risk human papillomavirus (HR-HPV) infection is the primary etiologic agent associated with the development ...
Efecto de miR-24 sobre YKL-40 en leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2021-01)
YKL-40 also known as CHI3L1 (Chitinase-3-like protein 1), is an inflammatory glycoprotein which is secreted by different cell types such as inflammatory cells. This protein is elevated in the serum or plasma of patients ...