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Análisis de la expresión de genes de adhesión en biopsias cervicales por efecto de las variantes de la oncoproteína E6 del VPH16
(Universidad Autónoma de Guerrero (México), 2018-01)
Cervical cancer (CaCU) is the most common neoplasm in women worldwide and the main etiologic factor is the persistent infection with AR-HPV. HPV16 genotype is associated with more than fifty percent of cases of CaCU. There ...
Efecto del resveratrol sobre la actividad de unión de los factores de transcripción Sp y NRF1 en un modelo in vivo de isquemia cerebral
(Universidad Autónoma de Guerrero (México), 2015-02)
Cerebral ischemia results from decreased blood flow due to obstruction or thrombosis of a major cerebral artery. This event can trigger cell death or cell survival pathways depending on various factors such as the concentration ...
Diversidad genética y perfil toxigénico de cepas del grupo Bacillus cereus aisladas de alimentos comercializados en el Estado de Guerrero
(Universidad Autónoma de Guerrero (México), 2014-11)
Species of the Bacillus cereus group is a set of sporulated microorganisms widely distributed in the environment, some of these species have been reported to cause emetic type food poisoning and / or diarrhea in different ...
Participación de PI3K y Rac1 en la Transición Epitelio-Mesenquimal inducida por leptina en células MCF10A
(Universidad Autónoma de Guerrero (México), 2016-06)
Epithelial-Mesenchymal Transition (EMT) is associated with the acquisition of pro-metastatic properties in breast cancer cells. Deregulation in the production of adipocytokines, particularly overproduction of leptin, has ...
Efecto del extracto de ajo envejecido sobre el nivel de especies reactivas de oxígeno y fosforilación de la AMPK en un modelo in vivo de diabetes
(Universidad Autónoma de Guerrero (México), 2017-01)
Hyperglycemia in diabetes is associated with long-term damage and dysfunction of organs such as eyes, kidney and heart. Hyperglycemia generates an increase in the production of reactive oxygen species and a decrease in ...
Efecto de la metilación de la LCR en la actividad transcripcional del VPH16
(Universidad Autónoma de Guerrero (México), 2015-01)
Experimental and epidemiological evidence suggests that CaCU is caused by persistent infection with high-risk HPV. Genotype 16 is the most commonly detected in CaCU. The E6 and E7 oncogenes largely explain the oncogenic ...
RNAs largos no codificantes (lncRNAs) y su relación con diabetes tipo 2
(Universidad Autónoma de Guerrero (México), 2019-01)
Type-2 diabetes (T2D) has been linked to different environmental, genetic and epigenetic factors. It has been described that the expression of H19, MALAT1 and MIAT is related to metabolic diseases such as metabolic syndrome, ...
Evaluación de la expresión de peroxiredoxina III, MCM2/TOP2a y su relación con el estado físico del VPH-AR en la carcinogénesis cervical
(Universidad Autónoma de Guerrero (México), 2018-01)
Squamous cell carcinoma (SCC) is causally related to the high-risk human papilloma virus (HR-HPV) oncoproteins E6 and E7, several studies have suggested the role of oxidative stress in the progression of a squamous ...
Evaluación de autoanticuerpos como marcadores de autoinmunidad en jóvenes universitarios con obesidad
(Universidad Autónoma de Guerrero (México), 2014-12)
Background. Obesity conditions a systemic inflammatory state, which promote alterations in regulatory lymphocytes subpopulations of immune tolerance, also dysregulated intracellular signaling for adipokines, mainly. Thus, ...
Polimorfismo -308G/A de TNF-alfa y genotipos babA2 y cagA de Helicobacter pylori en pacientes con gastritis crónica y úlcera gástrica
(Universidad Autónoma de Guerrero (México), 2010-03)
The infection by Helicobacter pylori cagA+/babA2+, is associated with several clinical outcomes, from a non atrophic gastritis and even gastric cancer. The polymorphism -308G/A of TNF-a (rs1800629) have been related with ...