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Modulación de la proliferación y supervivencia celular por la oncoproteína E6 de la variante E-G350 del VPH-16 en células HaCaT en respuesta a quimioterapia y radioterapia
(Universidad Autónoma de Guerrero (México), 2015-01)
E6 oncoprotein of HPV-16 alters cell proliferation, apoptosis, and the transcriptional regulation of several genes by binding to cellular proteins as E6AP, p53, Bax and caspase-8. Have been reported to E6 can bind and ...
Cambios morfológicos y expresión de ROR¿t y UBR5 en células mononucleares humanas infectadas con H. pylori.
(Universidad Autónoma de Guerrero (México), 2020-01)
H. pylori infection induces morphological alterations of gastric epithelial cells, infiltration of mononuclear cells and increase in the number of Th17 cells. Reported data show an increase in IL-17A due to the activation ...
Estudio longitudinal de la composición corporal y del perfil metabólico en personas positivas para Adenovirus 36.
(Universidad Autónoma de Guerrero (México), 2019-12)
Infectobesity refers to the implication that some microorganisms have in the development of obesity. Adenovirus 36 (Ad-36) has been linked to obesity in studies in human and animal models. Aim: We evaluated the relationship ...
Efecto crónico del cadmio sobre marcadores de transición epitelio-mesenquimal en células de epitelio mamario no tumoral.
(Universidad Autónoma de Guerrero (México), 2019-11)
Breast cancer (BC) is the most frequent neoplasia and leading cause of death in Mexican and worldwide women. Besides the well-known risk factors, the exposure to environmental hazards such as cadmium (Cd) is currently been ...
miR-24-3p y miR-142-3p: Expresión en pacientes con patología gástrica y relación con PKC en macrófagos humanos infectados por Helicobacter pylori.
(Universidad Autónoma de Guerrero (México), 2020-01)
H. pylori is the main cause of chronic gastritis and gastric cancer. In response to H. pylori, monocytes and macrophages are accumulate in the gastric mucosa, however, the bacteria is resistant to death by these cells. H. ...
Expresión de miR-26b, miR-100 y uno de sus genes blanco en células de leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2020-01)
MicroRNAs participate in the regulation of gene expression in multiple cellular processes, including leukemogenesis. miR-26b and miR-100 in acute lymphoblastic leukemia (ALL) have a deregulation in their expression. The ...
Efecto de E7 de referencia y de su variante C732/C789/G795 del VPH 16 sobre la expresión de las Isoformas de OCT4.
(Universidad Autónoma de Guerrero (México), 2019-12)
High-risk Human Papillomavirus (HPV-AR), such as HPV16, has been associated with the development of cervical cancer (CaCU). Several studies suggest that specific variations in the sequence of its oncogenes such as HPV E7 ...
Evaluación de la línea celular Huh7 como modelo de resistencia a la insulina determinado por diversos biomarcadores en comparación con HepG2.
(Universidad Autónoma de Guerrero (México), 2020-01)
Insulin resistance (RI) is defined as the inability of insulin to internalize glucose in its target cells, favoring the development of metabolic diseases. The liver plays an important role in the development of RI; hence, ...
Análisis de la expresión de pRb en células transfectadas con E7 de VPH 16 prototipo y sus variantes E7-A712, E7-G647/C789/G795 y E7-C732/C789/G795.
(Universidad Autónoma de Guerrero (México), 2020-12)
HPV 16 is the pathogen most associated with cervical cancer, a disease in which the overexpression of the viral oncoprotein E7 plays an essential role because its main targets are proteins involved in the regulation of the ...
Efecto de la disminución de HOTAIR en la metilación y expresión de los genes CDH3, ITGA8, HLA-DRA y VCAM1, que participan en adhesión celular, en la línea celular HeLa.
(Universidad Autónoma de Guerrero (México), 2020-01)
The lncRNA HOTAIR regulates gene expression through DNA methylation. HOTAIR is overexpressed in cervical cancer and modulates migration, invasion, proliferation, and apoptosis among other cellular processes. The migration ...