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Efecto de las variantes de la oncoproteína E6 del VPH16 en la apoptosis inducida por cisplatino
(Universidad Autónoma de Guerrero (México), 2019-01)
Several studies have been carried out that have analyzed the oncogenic potential of some variants of HPV16 and the deregulation of apoptosis. Demonstrating that the variants of the E6 oncoprotein of HPV16 and the E6 prototype ...
Polimorfismos t786c, g894t y g10t en el gen NOS3 y su relación con presión arterial alta en población guerrerense
(Universidad Autónoma de Guerrero (México), 2017-01)
Globally, one in three adults has high blood pressure. Nitric oxide (NO) is an endogenous free radical, involved in vasorelaxation, and therefore, in reducing vascular resistance and blood pressure. Nitric oxide is synthesized ...
Polimorfismos en el gen PON1 y daño al DNA en población expuesta ocupacionalmente a plaguicidas organofosforados
(Universidad Autónoma de Guerrero (México), 2014-06)
PON1 is an enzyme that hydrolyzes the active metabolites of OP (oxons). It has determined that single nucleotide polymorphisms (SNP) in the promoter (108CT) and coding (L55M and Q192R) region of PON1 gene induce variations ...
Efecto de la leptina recombinante sobre la producción de citocinas proinflamatorias (il-1, il-6 y tnf) en células mononucleares de sangre periférica con variantes polimórficas en el gen LEPR
(Universidad Autónoma de Guerrero (México), 2012-10)
Leptin is a hormone that regulates energy balance. In mononuclears cells promotes proinflammatory cytokine production such as IL-1, IL-6 y TNF. In the leptin receptor gene (LEPR), have been described various alterations, ...
Microbiota intestinal, su papel en la endotoxemia y en el perfil metabólico de jóvenes
(Universidad Autónoma de Guerrero (México), 2013-11)
The intestinal microbiota (MI) plays an important role in human metabolism, studies suggest that the imbalance can cause a metabolic endotoxemia impact on weight gain and insulin resistance. Analyze the association between ...
Diversidad de la región variable 3 del oncogén cagA de H. pylori en pacientes con gastritis crónica y cáncer gástrico
(Universidad Autónoma de Guerrero (México), 2013-09)
Chronic infection with Helicobacter pylori is associated with chronic gastritis, peptic ulcer and gastric cancer. Strains of H. pylori cagA-positive increases the risk of gastric pathology. The carcinogenic potential of ...
Efecto del resveratrol sobre el nivel de expresión de los transportadores de glucosa GLUT en isquemia cerebral in vivo
(Universidad Autónoma de Guerrero (México), 2014-01)
Ischemic stroke results from occlusion of a major cerebral artery and involves a cascade of metabolic events that begin during insult and proceed well into the blood flow recovery period [reperfusion (R)]. Impairment of ...
Expresión de p16INK4a, MCM2/TOPII y REST y estado físico del VPH 16 en el seguimiento de lesiones tempranas del cérvix uterino en mujeres guerrerenses
(Universidad Autónoma de Guerrero (México), 2019-01)
In Mexico, invasive cervical carcinoma (ICC) remains the second most frequent carcinoma in women [1]. Persistent High-Risk HPV infection (HR-HPV) is the main risk factor for cervical carcinogenesis [2]. The viral infection ...
Efecto de la sobreexpresión de miR-23b en los niveles de fosforilación de Gab1 y FAK vía c-Met y en la migración e invasión en líneas celulares de cáncer cervico uterino
(Universidad Autónoma de Guerrero (México), 2019-01)
Cervical uterine cancer (CaCU) is the second most frequent cancer in women and persistent infection by HPV-AR is the main risk factor for its onset. Epigenetic factors such as the deregulated expression of microRNAs (miRNAs) ...
Polimorfismos A-2570G, G-2081A, A896G y C1196T del gen TLR4 asociados con obesidad y alteraciones metabólicas en jóvenes universitarios
(Universidad Autónoma de Guerrero (México), 2018-01)
Obesity is a multifactorial disease characterized by a chronic lowgrade inflammatory process. Nowadays, genetic variations have been described in the TLR4 gene that can decrease or increase the response to lipopolysaccharide. ...