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Mostrando ítems 161-170 de 170
Polimorfismos y haplotipos en el gen PADI2 y su relación con la diversificación clínica en pacientes con artritis reumatoide del sur de México.
(Universidad Autónoma de Guerrero (México), 2020-12)
Rheumatoid arthritis (RA) is a progressive autoimmune disease characterized by inflammation, pain, and joint limitation. The citrullination is a process mediated by peptidyl arginine deiminase (PADI) enzymes and is recognized ...
Efecto antioxidante sobre niveles plasmáticos de grelina/leptina y daño oxidativo hipotalámico en ratas con diabetes.
(Universidad Autónoma de Guerrero (México), 2021-07)
The hormones ghrelin and leptin are important signal regulators of energy homeostasis from the periphery to the hypothalamus. Diabetic hyperphagia is the result of the intracellular energy imbalance that leads to a state ...
Caracterización in silico y molecular del LncRNA MINCR y su posible papel en la migración en células C33-A/AA-c de E6 del VPH-16.
(Universidad Autónoma de Guerrero (México), 2021-12)
Infection with human papillomavirus 16 (HPV-16) is one of the first events in the carcinogenesis process in cervical cancer (CC). The expression of the viral oncoprotein E6 and E7 is essential in this process to inactivate ...
Expresión de HIF-1A y genes blanco in vitro e in silico en cáncer cervicouterino.
(Universidad Autónoma de Guerrero (México), 2022-12)
Cervical cancer (CC) is the most common cancer in women in the lower genital tract. The main risk factor for developing CC is persistent infection with HPV 16. The E6 and E7 oncoproteins of HPV 16 have been related to ...
Resistencia a la insulina cerebral y su relación con la resistencia a la insulina periférica en un modelo in vivo de obesidad.
(Universidad Autónoma de Guerrero (México), 2021-06)
Introduction: Insulin resistance (IR) is a condition that characterizes metabolic disorders, such as obesity and type 2 diabetes mellitus, which causes insulin-dependent tissues to alter their metabolism due to lack of ...
Análisis de la interacción de E6-prototipo de VPH-16 y sus variantes E6-AAa y E6-AAc con MAGI 1 y el efecto en su degradación.
(Universidad Autónoma de Guerrero (México), 2021-11-05)
Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) 18 mediates the degradation of Membrane-associated guanylate kinase with inverted 19 domain structure-1 (MAGI-1), throughout the interaction of its protein binding ...
Efecto de la expresión de la oncoproteína E6 de las variantes AA-a, E-G350 y E-A176/G350 del VPH-16 en la metilación de genes relacionados con adhesión, migración e invasión celular.
(Universidad Autónoma de Guerrero (México), 2021-07)
Several studies have shown that DNA hypermethylation is one of the main alterations that occur with greater frequency in the establishment of cervical carcinoma. The VPH E6 oncoprotein has already been shown to promote the ...
Análisis de la expresión de las isoformas de OCT4 y su significado clínico en leucemias agudas.
(Universidad Autónoma de Guerrero (México), 2021-07)
Introduction: Acute lymphoblastic leukemia (ALL) is characterized by the unregulated proliferation of B or T lymphoid precursor cells. Due to their ability to self-renewal, cancer stem cells (CSC) play a crucial role in ...
Análisis de la expresión de las proteínas no caracterizadas del cromosoma 19 en cáncer cervicouterino, mama y ovario: Proyecto Proteoma Humano (HUPO).
(Universidad Autónoma de Guerrero (México), 2022-12)
Introduction: Cancer is one of the leading causes of death worldwide, the origin of this disease is multifactorial and involves the deregulation of genetic, epigenetic, and proteomic processes, among others. The Human ...
Actividad antiproliferativa y antimigratoria de extractos orgánicos de Tagetes en líneas celulares de cáncer cervicouterino.
(Universidad Autónoma de Guerrero (México), 2021-02)
Background Tagetes species are widely used in traditional medicine and have been shown to exert diverse biological activities due to its phytochemical constituents, including those related to cancer. Objetives: The present ...