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Risk of progression of early cervical lesions is associated with Integration and persistence of HPV-16 and expression of E6, Ki-67, and telomerase)
(2015-09-04)
Low-grade squamous intraepithelial lesions (LSIL) are the earliest lesions of the uterine cervix, the persistence and integration of high-risk human papillomavirus (HR-HPV) as type 16, which promotes the development of ...
MicroRNA miR-16-1 regulates CCNE1 (cyclin E1) gene expression in human cervical cancer cells
(International Journal of Clinical and Experimental Medicine, 2015-09-30)
MicroRNAs are involved in diverse biological processes through regulation of gene expression. The microRNA profile has been shown to be altered in cervical cancer (CC). MiR-16-1 belongs to the miR-16 cluster and has been ...
Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells
(Virology, 2015-12-02)
We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned ...
miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
(Infectious Agents and Cancer, 2015-01)
The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ...
The gerW protein Is not involved in the germination of spores of bacillus species
(PLoS ONE, 2015-03-19)
Germination of dormant spores of Bacillus species is initiated when nutrient germinants bind to germinant receptors in spores' inner membrane and this interaction triggers the reléase of dipicolinic acid and cations from ...
The effects of heat activation on bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins
(Applied and Environmental Microbiology, 2015-02-13)
Nutrient germination of spores of Bacillus species occurs through germinant receptors (GRs) in spores'inner membrane (IM) in a process stimulated by sublethal heat activation. Bacillus subtilis spores maximum germination ...
Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México
(International Journal of Molecular Sciences, 2015-09-08)
Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ...
Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
(Virology Journal, 2015-02-22)
HPV 16 is the cause of cervical carcinoma, but only a small fraction of women with HPV infection progress to this pathology. Besides persistent infection and HPV integration, several studies have suggested that HPV intratype ...
Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT5 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects
(Hindawi Publishing Corporation, 2015-03-30)
We analyzed the relationship of -794 CATT5 and -173 G>C MIF polymorphisms with mRNA and soluble MIF in young obese. A total of 250 young subjects, 150 normal-weight and 100 obese subjects, were recruited in the study. ...
Correlation of leptin and soluble leptin receptor levels with anthropometric parameters in mother-newborn pairs
(International Journal of Clinical and Experimental Medicine, 2015-07-30)
The aim of this study was to investigate if anthropometric parameters are associated with both leptin and soluble leptin receptor (sLEPR) levels in newborns and their mothers. This cross-sectional study was performed in ...