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Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)
(2014-03-13)
Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus ...
Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México
(International Journal of Molecular Sciences, 2015-09-08)
Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ...
Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
(Virology Journal, 2015-02-22)
HPV 16 is the cause of cervical carcinoma, but only a small fraction of women with HPV infection progress to this pathology. Besides persistent infection and HPV integration, several studies have suggested that HPV intratype ...
Effects of sporulation conditions on the germination and germination protein levels of bacillus subtilis spores
(Applied and Environmental Microbiology, 2012-02-10)
Bacillus subtilis spores prepared in rich medium germinated faster with nutrient germinants than poor-medium spores as populations in liquid and multiple individual spores on a microscope slide. Poor-medium spores had ...
Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT5 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects
(Hindawi Publishing Corporation, 2015-03-30)
We analyzed the relationship of -794 CATT5 and -173 G>C MIF polymorphisms with mRNA and soluble MIF in young obese. A total of 250 young subjects, 150 normal-weight and 100 obese subjects, were recruited in the study. ...
Variaciones de número de copias: marcadores y predictores de diabetes tipo 2
(Revista Medica Instituto Mexicano Seguro Social, 2014-07-15)
Type 2 diabetes (T2D) is a disease characterized by a defi ciency in production or action of insulin. It is the result mainly of the interaction of the environment, lifestyle, as well as genetic factors. It is considered ...
Correlation of leptin and soluble leptin receptor levels with anthropometric parameters in mother-newborn pairs
(International Journal of Clinical and Experimental Medicine, 2015-07-30)
The aim of this study was to investigate if anthropometric parameters are associated with both leptin and soluble leptin receptor (sLEPR) levels in newborns and their mothers. This cross-sectional study was performed in ...
Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
(Clin Exp Pathol, 2017-10-15)
Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ...
CD36 haplotypes are associated with lipid profile in normal-weight subjects
(Lipids in Health and Disease, 2013-04-13)
Dyslipidemia is a common metabolic disorder that may result from abnormalities in the synthesis, processing and catabolism of lipoprotein particles. Disorders of lipoprotein concentrations and elevated concentration of ...
Nuclear expression of Rac1 in cervical premalignant lesions and cervical cáncer cells
(BMC Cancer, 2012-03-23)
Abnormal expression of Rho-GTPases has been reported in several human cancers. However, the expression of these proteins in cervical cancer has been poorly investigated. In this study we analyzed the expression of the ...