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Efecto de la sobre-expresión de DNMT3B en la actividad transcripcional de genes relacionados con el cáncer
(Universidad Autónoma de Guerrero (México), 2016-10)
Introduction: DNMT3B, de novo DNA methyltransferase, is frequently overexpressed in cancer. This event is associated with abnormal methylation of tumor suppressor and DNA repair genes, favoring the development and progression ...
Efecto de HOTAIR sobre TET1 y la vía WNT en la línea celular HeLa.
(Universidad Autónoma de Guerrero (México), 2020-01)
Hox transcript antisense intergenic RNA (HOTAIR) es un RNA no codificante largo (lncRNA) que se transcribe de la región 12q13.13, específicamente de la cadena antisentido en la región intergénica entre HOXC11 y HOXC12, y ...
Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
(BioMed Central, 2016-03-14)
Background: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins ...
HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
(Cellular Physiology and Biochemistry, 2019-12-05)
Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some ...
Antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with indium and iron
(Microbiology Research International, 2016-11)
The need for new antimicrobial compounds has drawn attention on developing new and emerging materials based on nanoparticles with antimicrobial activity. The aim of this research was to evaluate the antibacterial activity ...
Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects
(BioMed Central, 2015-09-13)
Background: Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and the relationship between diet and genes in the presence of other ...
Efecto de los antioxidantes sobre la expresión de moléculas que regulan la conducta alimentaria en ratas diabéticas.
(Universidad Autónoma de Guerrero (México), 2019-06)
To establish a representative DM model that present most of the characteristics of the disease; and to evaluate if antioxidants can regulate diabetic hyperphagia and determine if this is related to the change in the ...
A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile
(International Journal of Immunopathology and Pharmacology, 2020-12-21)
The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic ...
Resistencia a la insulina inducida por exposición a metamidofos: participación del estrés oxidativo.
(Universidad Autónoma de Guerrero (México), 2018-01-01)
induction of oxidative stress is a mechanism through which OP induces IR. The objective of this work was to evaluate whether MET is capable to generate IR in HepG2 cells. In addition, we investigated the relationship between ...
Análisis estructural y funcional de las variantes génicas E7 del VPH 16 presentes en muestras cervicales de mujeres del estado de Guerrero.
(Universidad Autónoma de Guerrero (México), 2021-06)