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KIR/HLA Gene Profile Implication in Systemic Sclerosis Patients from Mexico.
(Hindawi, 2019-01-06)
Systemic Sclerosis (SSc) is an autoimmune, inflammatory, and multisystemic disease characterized by the presence of autoantibodies and fibrosis. The pathogenesis involves the interaction between immune system cells such ...
Association Between the 5,10-MTHFR 677C>T and RFC1 80G>A Polymorphisms and Acute Lymphoblastic Leukemia.
(ELSEVIER, 2019-05)
Polymorphisms in folate-related genes are closely related to the development of cancer. The 5,10-MTHFR 677C>T and RFC1 80G>A polymorphisms are associated with an increased risk of susceptibility to pediatric ALL.
Terminal Deoxynucleotidyl Transferase in type B Acute Lymphoblastic Leukemia.
(Avens Publishing, 2019-02)
Terminal deoxynucleotidyl transferase (TdT or DNTT) is a nuclear enzyme whose expression is restricted to normal tissue (thymus and bone marrow) and to lymphoid precursors of the B and T cell. TdT catalyzes the addition ...
The encounter with nature at an early age, a case in environmental education as a strategy for a better future.
(Journal of Science, 2016-01)
In the socio-environmental context; the students and teacher are willing to venture into the construction of knowledge, an early age a strategy of environmental health for narrative in social context strategy. The objective ...
Association of extrapituitary prolactin promoter polymorphism with disease susceptibility and anti-RNP antibodies in Mexican patients with systemic lupus erythematosus.
(Archives of Medical Science, 2016-06-21)
Prolactin (PRL) is a 23-kDa protein that can be synthesized and secreted by pituitary and extrapituitary tissues such as immune cells due to its expression being regulated by two independent promoter regions. The promoter ...
A possible association between the -2518 A>G MCP-1 polymorphism and insulin resistance in school children.
(SCIELO, 2017-08-09)
Objective: Monocyte chemoattractant protein 1 (MCP-1) has been suggested to be involved in the pathophysiology of insulin resistance (IR); therefore, variants in the MCP-1 gene may contribute to the development of this ...
PTPN22 1858C>T polymorphism is associated with increased CD154 expression and higher CD4+ T cells percentage in rheumatoid arthritis patients.
(Journal Clinical Laboratory Analysis, 2018-10-14)
Background: CD40 is a costimulatory molecule for B cells, and CD154 is a marker of CD4+ T cells activation. CD40 CD154 interaction promotes pro¿inflammatory cytokines secretion and autoantibodies production. PTPN22 gene ...
vacA s1m1 genotype and cagA EPIYA-ABC pattern are predominant among Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
(Medical Microbiology, 2017-11-30)
Purpose. Virulent genotypes of Helicobacter pylori vacA s1m1/cagA+/babA2+ have been associated with severe gastric diseases. VacA, CagA and BabA are polymorphic proteins, and their association with the disease is ...
MMP-2 salivary activity in type 2 diabetes mellitus patients
(Diabetology & Metabolic Syndrome, 2019-01)
Type 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirec¿ tional relationship. The uncontrolled levels of glucose in T2DM patients change the pathophysiology and balance of ...
The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
(BioMed Research International, 2017-10-10)