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Papel del polimorfismo G-308A y expresión del RNAm del TNF en la oncogénesis cervical
(Universidad Autónoma de Guerrero (México), 2008-06)The expression of proinflammatory cytokine, as the tumor necrosis factor alpha (TNF) in the site of a persistent infection with the human papilloma virus aid in a high oncogenic risk promotes the process of carcinogenesis ... -
Niveles de fosforilación en tirosina en eritrocitos de ratón balb c durante un proceso infeccioso provocado por yersinia pseudotuberculosis
(Universidad Autónoma de Guerrero (México), 2008-08)Yersinia pseudotuberculosis can penetrate cells in the intestinal epithelium and invades mesenteric lymph nodes, liver and spleen through invasin B1 integrin interaction. It has been shown in vitro experimental assays with ... -
Búsqueda de receptores a glutamato en el cisticerco
(Universidad Autónoma de Guerrero (México), 2008-08)Human cysticercosis is caused by Taenia solium larvae that infects tissues and organs becoming an important health problem among several undeveloped countries. The presence of T. Solium in central nervous system (CNS) is ... -
Péptidos recombinantes de Trypanosoma cruzi y su utilidad en el diagnóstico de la enfermedad de chagas en el Estado de Guerrero
(Universidad Autónoma de Guerrero (México), 2008-10)Background: Diagnosis of Chagas disease is based on serological methods with high occurrence of false positive. The use of recombinant antigens is recommended to increase the sensitivity and specificity of serological ... -
Polimorfismos -174 gc y -572 gc en el gen de interleucina 6 y su asociación con factores de riesgo cardiovascular en familias con obesidad
(Universidad Autónoma de Guerrero (México), 2008-10)The family studies have demonstrated the genetic influence in the development of traditional cardiovascular risk factors. Interleukin-6 (IL-6) is a cytokine involved in inflammatory process, as well as in the glucose and ... -
Resistencia primaria y secundaria de virus libre en plasma e integrado en células mononucleares de sangre periférica en personas con VIH de Guerrero
(Universidad Autónoma de Guerrero (México), 2008-10)Antiretroviral (ARV) drug resistance causes treatment failure in persons with HIV and can be transmitted to individuals without previous ARV treatment. Objective: To determine and compare the frequency of primary and ... -
Validación de dos variantes de la técnica rep-PCR para la tipificación molecular de aislamientos clínicos de Enterobacter cloacae productores de lactamasas de espectro extendido
(Universidad Autónoma de Guerrero (México), 2008-10)The use of molecular techniques in the epidemiology of infectious diseases allows us to determine the existed clonal relationship between several isolated from the same species; this information is especially useful when ... -
Expresión de p16ink4a en lesiones premalignas de bajo grado con infección por Virus del Papiloma Humano
(Universidad Autónoma de Guerrero (México), 2008-12)Background. The protein p16INK4a is an inhibitor of cyclin-dependent kinases (CDKs) that slows the cell cycle by inactivating CDKs involved in the phosphorylation of the retinoblastoma protein (pRb). Infection with high-risk ... -
Niveles IFN E IL-4 en niños expuestos ambientalmente a metales en una zona minera
(Universidad Autónoma de Guerrero (México), 2008-12)The metals released from mining waste (tailings) are environmental pollutants that represent potential risks to health, especially for vulnerable populations such as children. Cytokines are soluble proteins, regulators of ... -
Helicobacter pylori y polimorfismos 511 ct y 31tc de la il-1b en pacientes con gastritis crónica y úlcera gástrica
(Universidad Autónoma de Guerrero (México), 2009-01)The genotype vacA s1m1 of H. pylori is associate with the inflammation induction and damage in the gastric mucosa. In people with the polymorphisms 511 CT and -31 TC the IL1B the infection with this genotype of Helicobacter ... -
Análisis de metilación del ADN de VPH 16 integrado al genoma celular
(Universidad Autónoma de Guerrero (México), 2009-01)Background. Loss of gene expression regulation is a key characteristic of cancer; epigenetic modifications alter gene expression and thus play an important role in carcinogenesis. Integration of viral DNA in persistent ... -
Análisis proteómico del intestino del mosquito Aedes aegypti durante la hematofagia
(Universidad Autónoma de Guerrero (México), 2009-01)The purpose of this study was to identify proteins from the midgut of Ae. aegypti, whose expression is changed by the hematophagy and others that are constituents of cell membranes. Materials and methods. Midguts of ... -
Polimorfismo 62 GA en la región 3UTR del gen retn y niveles sanguíneos de la resistina en pacientes con diabetes tipo 2
(Universidad Autónoma de Guerrero (México), 2009-06)Resistin is a proteic hormone secreted mainly by adipose tissue. It has been suggested a possible role of the resistin in the glucose metabolism. In mouse models, resistin overexpression produce a diminished sensitivity ... -
Polimorfismos de la dnmt3b y su asociación con el desarrollo de lesiones precancerosas y cáncer cérvico uterino
(Universidad Autónoma de Guerrero (México), 2009-06)Epigenetic and genetic factors are important for the development of cervical cancer (CC). DNMT3B plays a crucial role in carcinogenesis, its novo metilase activity can lead to silencing of tumor suppressor genes. Polymorphic ... -
Polimorfismos +1444 c/t y +1846 g/a del gen de la proteína C reactiva y su asociación con los niveles de su proteína en personas con obesidad
(Universidad Autónoma de Guerrero (México), 2009-08)Several single nucleotide polymorphisms (SNPs) in the C reactive protein gene (CRP) have been associated with increase serum concentration of their protein, some of them have been correlated with cardiovascular disease. ... -
Participación de mTOR en la regulación del transportador EAAC1 en células C6 de Glioma
(Universidad Autónoma de Guerrero (México), 2009-08)Glutamate (Glu) is the major excitatory neurotransmitter in the vertebrate central nervous system (CNS); it is involved in neural plasticity as well in learning and memory. Neuronal and glial sodium-dependent transporters ... -
Polimorfismos en el gen de la y-glutamil hidrolasa y respuesta al metotrexato en leucemia linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)This study evaluated the association of -401C/T and +452C/T polymorphisms of y-glutamyl hydrolase and the lack of response to methotrexate in acute lymphoblastic leukemia. Genotyping was performed 70 children with acute ... -
Polimorfismos en el gen de la Dihidrofolato Reductasa y respuesta al Metotrexato en Leucemia Linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)The presence of polymorphisms in regulatory regions causes increased expression of dihydrofolate reductase (DHFR), and it is associated with methotrexate (MTX) treatment adverse events. A case control study was conducted ... -
GTPasas RhoA, Rac1 y Cdc42 y los GEFs Tiam1 y BPix en el desarrollo de cáncer cervicouterino
(Universidad Autónoma de Guerrero (México), 2009-09)Cervical cancer is an important health problem and one of the major causes of mortality in Mexico particularly in some states with high rates of exclusion, including the state of Guerrero. Fortunately, advances in molecular ... -
Polimorfismos A19G en el gen de leptina y A668G en su receptor y su relación con las concentraciones de leptina sérica y la hiperfagia en niños con obesidad
(Universidad Autónoma de Guerrero (México), 2009-09)Leptin is an anorexigenic hormone that controls food intake and energy homeostasis, which by binding to its receptors in the hypothalamus, releases signals that generates a feeling of satiety, regulating appetite and weight ...