A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile
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2020-12-21Autor
Bautista Herrera, Luis Alberto
De La Cruz Mosso, Ulises
Roman Fernandez, Ilce Valeria
Parra Rojas, Isela
Soñanez Organis, José Guadalupe
Hernandez Bello, Jorge
Morales Zambrano, Ramses Alejandro
Villanueva Quintero, Delfina Guadalupe
Muñoz Valle, Jose Francisco
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The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic arthritis (PsA) patients. This cross-sectional study was conducted in 50 patients with PsA and 30 control subjects (CS) matched by age and gender. The cytokine serum levels were quantified by magnetic bead - based assay using the Bio-Plex MAGPIX system, and RORC mRNA expression was determined by quantitative polymerase chain reaction (qPCR).
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