Multiple infections by EBV, HCMV and Helicobacter pylori are highly frequent in patients with chronic gastritis and gastric cancer from Southwest Mexico.

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Date
2019-12
Author
Del Moral Hernandez, Oscar
Castañon Sanchez, Carlos Alberto
Reyes Navarrete, Salomón
Martinez Carrillo, Dinorah Nashely
Betancourt Linares, Reyes
Jimenez Wences, Hilda
De La Peña Cruz, Carmen Sol
Roman Roman, Adolfo
Hernandez Sotelo, Daniel
Fernandez Tilapa, Gloria
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Abstract
The chronic inflammation and damage to the gastric epithelium induced by Helicobacter pylori (H. pylori) are the main risk factors for gastric cancer development. Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) induce chronic inflammation and have been found in gastric tumors. The objectives this observational study were to determine the frequency of multiple infections by Helicobacter pylori, Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) and to relate the infection by EBV and HCMV with H. pylori vacA/cagA genotypes in patients with chronic gastritis or gastric cancer. DNA from H. pylori, EBV and HCMV was detected by PCR in biopsies from 106 Mexican patients with chronic gastritis and 32 from gastric cancer.
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http://ri.uagro.mx/handle/uagro/1217
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http://creativecommons.org/licenses/by-nc-nd/4.0
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0