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dc.contributor.authorMachado Sulbaran, Andrea Carolina
dc.contributor.authorRamirez-Dueñas, Maria Guadalupe
dc.contributor.authorNavarro Zarza, Jose Eduardo
dc.contributor.authorMuñoz_Valle, José Francisco
dc.contributor.authorMendoza Carrera, Francisco
dc.contributor.authorBaños Hernandez, Christian Johana
dc.contributor.authorParra_Rojas, Isela
dc.contributor.authorMontoya Buelna, Margarita
dc.contributor.authorSanchez Hernandez, Pedro Ernesto
dc.creatorMACHADO SULBARAN, ANDREA CAROLINA; 660324
dc.creatorRamirez-Dueñas, Maria Guadalupe;#0000-0001-8066-5966
dc.creatorNAVARRO ZARZA, JOSE EDUARDO; 257698
dc.creatorMuñoz_Valle, José Francisco;#0000-0002-2272-9260
dc.creatorMendoza Carrera, Francisco;#0000-0002-0786-988X
dc.creatorBAÑOS HERNANDEZ, CHRISTIAN JOHANA; 560787
dc.creatorParra_Rojas, Isela;#0000-0002-9213-8263
dc.creatorMontoya Buelna, Margarita;#0000-0001-9309-1957
dc.creatorSanchez Hernandez, Pedro Ernesto;#0000-0001-5047-8115
dc.date.accessioned2020-04-21T23:31:38Z
dc.date.available2020-04-21T23:31:38Z
dc.date.issued2019-01-06
dc.identifier.issnhttps://doi.org/10.1155/2019/6808061
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1222
dc.description.abstractSystemic Sclerosis (SSc) is an autoimmune, inflammatory, and multisystemic disease characterized by the presence of autoantibodies and fibrosis. The pathogenesis involves the interaction between immune system cells such as macrophages, NK cells, T cells, and B cells. Killer-cell Immunoglobulin-like Receptors (KIR) are expressed in NK cells and some T cell subsets that recognize HLA class I molecules as ligands and are involved in regulating the activation and inhibition of these cells. The KIR family consists of 14 genes and two pseudogenes; according to the gene content, the genotype could be AA and Bx.
dc.formatpdf
dc.language.isospa
dc.publisherHindawi
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::OTRAS ESPECIALIDADES MÉDICAS
dc.titleKIR/HLA Gene Profile Implication in Systemic Sclerosis Patients from Mexico.
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3299
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y ciencias de la Salud
dc.identifier.cvuagro08201284


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