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Tumor suppressor miR-29c regulates radioresistance in lung cancer cells
(Tumor Biology, 2017-03)Radiotherapy is an important treatment option for non-small cell lung carcinoma patients. Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of cancer cells that limits the efficacy of ... -
Antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with indium and iron
(Microbiology Research International, 2016-11)The need for new antimicrobial compounds has drawn attention on developing new and emerging materials based on nanoparticles with antimicrobial activity. The aim of this research was to evaluate the antibacterial activity ... -
Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
(BioMed Central, 2016-03-14)Background: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins ... -
Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects
(BioMed Central, 2015-09-13)Background: Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and the relationship between diet and genes in the presence of other ... -
HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
(Cellular Physiology and Biochemistry, 2019-12-05)Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some ... -
A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile
(International Journal of Immunopathology and Pharmacology, 2020-12-21)The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic ... -
CD36 haplotypes are associated with lipid profile in normal-weight subjects
(Lipids in Health and Disease, 2013-04-13)Dyslipidemia is a common metabolic disorder that may result from abnormalities in the synthesis, processing and catabolism of lipoprotein particles. Disorders of lipoprotein concentrations and elevated concentration of ... -
Nuclear expression of Rac1 in cervical premalignant lesions and cervical cáncer cells
(BMC Cancer, 2012-03-23)Abnormal expression of Rho-GTPases has been reported in several human cancers. However, the expression of these proteins in cervical cancer has been poorly investigated. In this study we analyzed the expression of the ... -
miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
(Infectious Agents and Cancer, 2015-01)The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ... -
Diversidad de los genotipos vacA y cagA de helicobacter pylori y expresión de interferón gamma en pacientes con gastritis crónica y cáncer gástrico
(Revista de Gastroenterología de México, 2014-11-26)Background: Helicobacter pylori (H. pylori) is the main risk factor for the development of chronic gastritis, gastric ulcer, and gastric cancer. In H. pylori-infected individuals, the clinical result is dependent on various ... -
The gerW protein Is not involved in the germination of spores of bacillus species
(PLoS ONE, 2015-03-19)Germination of dormant spores of Bacillus species is initiated when nutrient germinants bind to germinant receptors in spores' inner membrane and this interaction triggers the reléase of dipicolinic acid and cations from ... -
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
(American Journal of Cancer Research, 2017-01)Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ... -
Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells
(Virology, 2015-12-02)We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned ... -
Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions
(Oncology Letters, 2017-09-13)High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ... -
Effects of sporulation conditions on the germination and germination protein levels of bacillus subtilis spores
(Applied and Environmental Microbiology, 2012-02-10)Bacillus subtilis spores prepared in rich medium germinated faster with nutrient germinants than poor-medium spores as populations in liquid and multiple individual spores on a microscope slide. Poor-medium spores had ... -
The effects of heat activation on bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins
(Applied and Environmental Microbiology, 2015-02-13)Nutrient germination of spores of Bacillus species occurs through germinant receptors (GRs) in spores'inner membrane (IM) in a process stimulated by sublethal heat activation. Bacillus subtilis spores maximum germination ... -
Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México
(International Journal of Molecular Sciences, 2015-09-08)Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ... -
Correlation of leptin and soluble leptin receptor levels with anthropometric parameters in mother-newborn pairs
(International Journal of Clinical and Experimental Medicine, 2015-07-30)The aim of this study was to investigate if anthropometric parameters are associated with both leptin and soluble leptin receptor (sLEPR) levels in newborns and their mothers. This cross-sectional study was performed in ... -
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)
(2014-03-13)Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus ... -
Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico
(Virology Journal, 2015-02-22)HPV 16 is the cause of cervical carcinoma, but only a small fraction of women with HPV infection progress to this pathology. Besides persistent infection and HPV integration, several studies have suggested that HPV intratype ...
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