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dc.contributor.authorCahua Pablo, Jose Angel
dc.contributor.authorMéndez Palacios, Abigael
dc.contributor.authorAntúnez Ortiz, Diana Lizzete
dc.contributor.authorVences Velázquez, Amalia
dc.contributor.authorAlarcón Romero, Luz Del Carmen
dc.contributor.authorTello Flores, Vianet Argelia
dc.contributor.authorLeyva Vazquez, Marco Antonio
dc.contributor.authorPérez Macedonio, Claudia Paola
dc.contributor.authorFlores Alfaro, Eugenia
dc.creatorCahua Pablo, Jose Angel; 333939
dc.creatorMéndez Palacios, Abigael; 484235
dc.creatorAntúnez Ortiz, Diana Lizzete; 368564
dc.creatorVences Velázquez, Amalia; 265192
dc.creatorAlarcón Romero, Luz Del Carmen; 259901
dc.creatorTello Flores, Vianet Argelia; 667004
dc.creatorLeyva Vazquez, Marco Antonio; 264272
dc.creatorPérez Macedonio, Claudia Paola; 705009
dc.creatorFlores Alfaro, Eugenia; 224947
dc.date.accessioned2019-04-04T00:02:01Z
dc.date.available2019-04-04T00:02:01Z
dc.date.issued2015-09-08
dc.identifier.issn1422-0067
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/400
dc.description.abstractMetabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes and MetS. Our aim was to evaluate the association between variants in ESR1, LPL and CETP genes with MetS and its components. Four hundred and eighty women were analyzed, anthropometric features and biochemical profiles were evaluated, and genotyping was performed by real-time PCR. We found an association with elevated glucose levels (odds ratio (OR) = 2.9; p = 0.013) in carrying the AA genotype of rs1884051 in the ESR1 gene compared with the GG genotype, and the CC genotype of rs328 in the LPL gene was associated with MetS compared to the CG or GG genotype
dc.description.sponsorshipThis research was supported by the Secretariat of Public Education of Mexico, through the Programa Integral de Fortalecimiento Institucional/Programa de Mejoramiento del Profesorado (PIFI, PROMEP)/103.5/12/3616. During the study José Ángel Cahua-Pablo was a grant recipient of theConsejo Nacional de Ciencia y Tecnología (CONACyT) of Mexico.
dc.formatpdf
dc.language.isoeng
dc.publisherInternational Journal of Molecular Sciences
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4
dc.subjectCAB Thesaurus /Metabolic síndrome
dc.subjectCAB Thesaurus /Polymorphisms
dc.subjectCAB Thesaurus /ESR1 haplotype
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::BIOLOGÍA HUMANA
dc.titlePolymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México
dc.typeArtículo
dc.contributor.committeeMemberCruz, Miguel
dc.contributor.committeeMemberParra, Esteban Juan
dc.contributor.committeeMemberValladares Salgado, Adán
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||2410
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro12300028
dc.identifier.doihttps://doi.org/10.3390/ijms160921539


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