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dc.contributor.authorMarino Ortega, Linda Anahi
dc.contributor.authorGuzmán Guzmán, Iris Paola
dc.contributor.authorParra Rojas, Isela
dc.creatorMarino Ortega, Linda Anahi; 333972
dc.creatorGuzmán Guzmán, Iris Paola; 210828
dc.creatorParra Rojas, Isela; 39755
dc.date.accessioned2019-04-04T00:02:01Z
dc.date.available2019-04-04T00:02:01Z
dc.date.issued2015-07-30
dc.identifier.issn1940-5901
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/401
dc.description.abstractThe aim of this study was to investigate if anthropometric parameters are associated with both leptin and soluble leptin receptor (sLEPR) levels in newborns and their mothers. This cross-sectional study was performed in 118 mother-newborn pairs. The venous blood sample of mothers was taken before delivery and immediately after delivery an umbilical cord blood sample was collected. Levels of leptin and sLEPR in maternal and umbilical cord sera were assessed by ELISA. Maternal serum concentration of leptin and sLEPR (6.2 and 25.7 ng/ml, respectively) were higher than in umbilical cord blood (2.4 and 14.2 ng/ml, respectively). However, the newborns and their moth¬ers had higher sLEPR levels than leptin levels. In mothers was observed that leptin levels increase with weight gain in pregnancy and decreased sLEPR levels. Cord leptin levels correlated with neonatal birth weight and length, the body circumferences, placental weight and maternal leptin levels. Cord sLEPR levels correlated with maternal sLEPR and leptin levels. Maternal serum concentration of leptin correlated with pre-pregnancy BMI, weight gain, cord sLEPR and leptin levels. Maternal sLEPR concentration correlated with cord sLEPR levels. The leptin and sLEPR levels in mother-newborn pairs are related with anthropometric parameters and an inverse correlation between leptin levels and sLEPR was observed in pairs.
dc.description.sponsorshipThis study was supported by Grants from the Consejo Nacional de Ciencia y Tecnología INFR-2014-02/229958 and Programa de Fortalecimiento Académico del Posgrado de Alta Ca- lidad 2013 and 2014. LAMO received a fellowship of CONACYT (No. 231241).
dc.formatpdf
dc.language.isoeng
dc.publisherInternational Journal of Clinical and Experimental Medicine
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4
dc.subjectCAB Thesaurus /Leptin, soluble receptor leptin
dc.subjectCAB Thesaurus /Neonate
dc.subjectCAB Thesaurus /Umbilical cord
dc.subjectCAB Thesaurus /Placenta
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::BIOLOGÍA HUMANA
dc.titleCorrelation of leptin and soluble leptin receptor levels with anthropometric parameters in mother-newborn pairs
dc.typeArtículo
dc.contributor.committeeMemberMolina Bello, Adiel
dc.contributor.committeeMemberPolanco García, Julio C
dc.contributor.committeeMemberMuñoz Valle, José F.
dc.contributor.committeeMemberSalgadoBernabé, Aralia B
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||2410
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro12300126


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