Artículos http://ri.uagro.mx/handle/uagro/21 2026-04-05T13:46:37Z Tumor suppressor miR-29c regulates radioresistance in lung cancer cells http://ri.uagro.mx/handle/uagro/1202 Tumor suppressor miR-29c regulates radioresistance in lung cancer cells Aréchaga Ocampo, Elena; Lopez Camarillo, Mario Cesar; Villegas Sepulveda, Nicolas; Gonzalez De La Rosa, Claudia Haydee; Perez Añorve, Isidro Xavier; Roldan Perez, Reynalda; Flores Perez, Jose Ali; Peña Curiel, Omar; Angeles Zaragoza, Oscar; Rangel Corona, Rosalva; Gonzalez Barrios, Juan Antonio; Bonilla Moreno, Raúl; Del Moral Hernandez, Oscar; Herrera, Luis A; Garcia Carranca, Alejandro Manuel Radiotherapy is an important treatment option for non-small cell lung carcinoma patients. Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of cancer cells that limits the efficacy of this treatment. Deregulation of microRNAs contributes to the molecular mechanism underlying resistance to radiotherapy in cancer cells. Although the functional roles of microRNAs have been well described in lung cancer, their functional roles in radioresistance are largely unclear. In this study, we established a non-small cell lung carcinoma Calu-1 radioresistant cell line by continuous exposure to therapeutic doses of ionizing radiation as a model to investigate radioresistance-associated microRNAs. 2017-03-01T00:00:00Z Antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with indium and iron http://ri.uagro.mx/handle/uagro/1201 Antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with indium and iron Castro Alarcon, Natividad; Herrera Arizmendi, Jose Luis; Luis Alberto, Marroquin Carteño; Guzman Guzman, Iris Paola; Perez Centeno, Armando; Santana Aranda, Miguel Angel The need for new antimicrobial compounds has drawn attention on developing new and emerging materials based on nanoparticles with antimicrobial activity. The aim of this research was to evaluate the antibacterial activity of nanoparticles of titanium dioxide, intrinsic and doped with Indium and Iron in Escherichia coli and Staphylococcus aureus. 2016-11-01T00:00:00Z Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells http://ri.uagro.mx/handle/uagro/1182 Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells Peralta Zaragoza, Oscar; Deas, Jessica; Meneses Acosta, Angelica; De La O Gomez, Faustino; Fernandez Tilapa, Gloria; Gomez Ceron, Claudia; Benitez Boijseauneau, Odelia; Burguete Garcia, Ana Isabel; Torres Poveda, Kirvis Janneth; Bermúdez Morales, Victor Hugo; Madrid Marina, Vicente; Rodriguez Dorantes, Mauricio; Hidalgo Miranda, Alfredo; Perez Plasencia, Carlos Guadalupe Background: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins in various signaling pathways, miR-21 is an attractive target for genetic and pharmacological modulation in various cancers. Cervical cancer is the second most common cause of death from cancer in women worldwide and persistent HPV infection is the main etiologic agent. This malignancy merits special attention for the development of new treatment strategies. In the present study we analyze the role of miR-21 in cervical cancer cells. 2016-03-14T00:00:00Z Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects http://ri.uagro.mx/handle/uagro/1181 Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects Dominguez Reyes, Teresa; Astudillo Lopez, Constanza Cecilia; Guzman Guzman, Iris Paola; Salgado Goytia, Lorenzo; Castro Alarcon, Natividad; Moreno Godinez, Ma. Elena; Muñoz Valle, Jose Francisco; Parra Rojas, Isela; Salgado Bernabé, Aralia B Background: Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and the relationship between diet and genes in the presence of other chronic diseases such as obesity. The objective of this study was to analyze the interaction of a high fat diet with the APOA2 (rs3813627 and rs5082), APOA5 (rs662799 and rs3135506) and LEPR (rs8179183 and rs1137101) polymorphisms and its relationship with obesity and dyslipidemia in young subjects. 2015-09-13T00:00:00Z