Browsing by Author "Llamas Covarrubias, Mara Anais"

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PTPN22 1858C>T polymorphism is associated with increased CD154 expression and higher CD4+ T cells percentage in rheumatoid arthritis patients.

Ruiz Noa, Yeniley; Hernandez Bello, Jorge; Llamas Covarrubias, Mara Anais; Palafox Sanchez, Claudia Azucena; Oregon Romero, Edith; Sánchez Hernández, Pedro Ernesto; Ramirez Dueñas, Maria Guadalupe; Parra Rojas, Isela; Muñoz Valle, Jose Francisco (Journal Clinical Laboratory Analysis, 2018-10-14)

Background: CD40 is a costimulatory molecule for B cells, and CD154 is a marker of CD4+ T cells activation. CD40 CD154 interaction promotes pro¿inflammatory cytokines secretion and autoantibodies production. PTPN22 gene ...