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Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells

dc.contributor.authorPeralta Zaragoza, Oscar
dc.contributor.authorDeas, Jessica
dc.contributor.authorMeneses Acosta, Angelica
dc.contributor.authorDe La O Gomez, Faustino
dc.contributor.authorFernandez Tilapa, Gloria
dc.contributor.authorGomez Ceron, Claudia
dc.contributor.authorBenitez Boijseauneau, Odelia
dc.contributor.authorBurguete Garcia, Ana Isabel
dc.contributor.authorTorres Poveda, Kirvis Janneth
dc.contributor.authorBermúdez Morales, Victor Hugo
dc.contributor.authorMadrid Marina, Vicente
dc.contributor.authorRodriguez Dorantes, Mauricio
dc.contributor.authorHidalgo Miranda, Alfredo
dc.contributor.authorPerez Plasencia, Carlos Guadalupe
dc.creatorPERALTA ZARAGOZA, OSCAR; 122021
dc.creatorMeneses Acosta, Angelica;#0000-0003-2677-4939
dc.creatorDE LA O GOMEZ, FAUSTINO; 333146
dc.creatorFERNANDEZ TILAPA, GLORIA; 90223
dc.creatorGOMEZ CERON, CLAUDIA; 512748
dc.creatorBURGUETE GARCIA, ANA ISABEL; 202724
dc.creatorTORRES POVEDA, KIRVIS JANNETH;#0000-0002-9050-2148
dc.creatorBermúdez Morales, Victor Hugo;#0000-0003-1165-3333
dc.creatorMadrid Marina, Vicente; 8157
dc.creatorRODRIGUEZ DORANTES, MAURICIO; 121410
dc.creatorHIDALGO MIRANDA, ALFREDO; 121473
dc.creatorPEREZ PLASENCIA, CARLOS GUADALUPE; 201014
dc.date.accessioned2020-04-09T21:59:19Z
dc.date.available2020-04-09T21:59:19Z
dc.date.issued2016-03-14
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1182
dc.description.abstractBackground: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins in various signaling pathways, miR-21 is an attractive target for genetic and pharmacological modulation in various cancers. Cervical cancer is the second most common cause of death from cancer in women worldwide and persistent HPV infection is the main etiologic agent. This malignancy merits special attention for the development of new treatment strategies. In the present study we analyze the role of miR-21 in cervical cancer cells.
dc.description.sponsorshipThis article was carried out at the Research Center in Infection Diseases of National Institute of Public Health from México (INSP). This article received funding sources from INSP, as well as from the National Council of Science and Technology (CONACYT) with file numbers: SALUD-2008-01-87130, SALUD-2009-01-111892 and CB-2011-01-169209. Thanks by technical support to Lorena Uribe-Toledo and Carlos A. Tavira-Montalván.
dc.formatpdf
dc.language.isoeng
dc.publisherBioMed Central
dc.rights.urihttp://creativecommons.org/licenses/by/4.0
dc.subjectCervical cancer
dc.subjectmicroRNAs
dc.subjectPTEN
dc.subjectsiRNAs
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::OTRAS ESPECIALIDADES MÉDICAS
dc.titleRelevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3299
dc.format.digitalOriginDigital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMEDICINA Y CIENCIAS DE LA SALUD
dc.identifier.cvuagro5783


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