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Efecto de la disminución de HOTAIR en la hidroximetilación global en la línea celular HeLa.

dc.contributorHernandez Sotelo, Daniel
dc.contributor.advisorHERNANDEZ SOTELO, DANIEL; 259435
dc.contributor.authorAdame Guerrero, Olga
dc.creatorADAME GUERRERO, OLGA; 777276
dc.date.accessioned2020-07-02T16:48:11Z
dc.date.available2020-07-02T16:48:11Z
dc.date.issued2019-01
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1521
dc.description.abstractGenetic and epigenetic alterations lead to the initiation and development of cancer. Epigenome of cancer cell is characterized by aberrant methylation of tumor suppressor genes, the functional consequence is the transcriptional repression of these genes. New evidence suggests an important role for long non-coding RNAs as modulators of the establishment of DNA methylation. HOTAIR represses the expression of tumor suppressor genes by establishing H3K27me3 and DNA methylation in promoter regions.
dc.formatpdf
dc.language.isospa
dc.publisherUniversidad Autónoma de Guerrero (México)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectlncRNA
dc.subjectmethylation
dc.subjectHOTAIR
dc.subjectHydroxymethylation
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::BIOQUÍMICA
dc.titleEfecto de la disminución de HOTAIR en la hidroximetilación global en la línea celular HeLa.
dc.typeTesis de maestría
dc.contributor.committeeMemberIliades Aguiar, Berenice
dc.contributor.committeeMemberDel Moral Hernández, Oscar
dc.contributor.committeeMemberCastañeda Saucedo, Eduardo
dc.contributor.committeeMemberHidalgo Miranda, Alfredo
dc.type.conacytmasterThesis
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||2302
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelMaestría
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro16261456


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0