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Efecto de la disminución de HOTAIR en la hidroximetilación global en la línea celular HeLa.
dc.contributor | Hernandez Sotelo, Daniel | |
dc.contributor.advisor | HERNANDEZ SOTELO, DANIEL; 259435 | |
dc.contributor.author | Adame Guerrero, Olga | |
dc.creator | ADAME GUERRERO, OLGA; 777276 | |
dc.date.accessioned | 2020-07-02T16:48:11Z | |
dc.date.available | 2020-07-02T16:48:11Z | |
dc.date.issued | 2019-01 | |
dc.identifier.uri | http://ri.uagro.mx/handle/uagro/1521 | |
dc.description.abstract | Genetic and epigenetic alterations lead to the initiation and development of cancer. Epigenome of cancer cell is characterized by aberrant methylation of tumor suppressor genes, the functional consequence is the transcriptional repression of these genes. New evidence suggests an important role for long non-coding RNAs as modulators of the establishment of DNA methylation. HOTAIR represses the expression of tumor suppressor genes by establishing H3K27me3 and DNA methylation in promoter regions. | |
dc.format | ||
dc.language.iso | spa | |
dc.publisher | Universidad Autónoma de Guerrero (México) | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0 | |
dc.subject | lncRNA | |
dc.subject | methylation | |
dc.subject | HOTAIR | |
dc.subject | Hydroxymethylation | |
dc.subject.classification | MEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::BIOQUÍMICA | |
dc.title | Efecto de la disminución de HOTAIR en la hidroximetilación global en la línea celular HeLa. | |
dc.type | Tesis de maestría | |
dc.contributor.committeeMember | Iliades Aguiar, Berenice | |
dc.contributor.committeeMember | Del Moral Hernández, Oscar | |
dc.contributor.committeeMember | Castañeda Saucedo, Eduardo | |
dc.contributor.committeeMember | Hidalgo Miranda, Alfredo | |
dc.type.conacyt | masterThesis | |
dc.rights.acces | openAccess | |
dc.audience | generalPublic | |
dc.identificator | 3||32||2302 | |
dc.format.digitalOrigin | Born digital | |
dc.thesis.degreelevel | Maestría | |
dc.thesis.degreename | Doctorado en Ciencias Biomédicas | |
dc.thesis.degreegrantor | Universidad Autónoma de Guerrero | |
dc.thesis.degreedepartment | Facultad de Ciencias Químico Biológicas | |
dc.thesis.degreediscipline | Medicina y Ciencias de la Salud | |
dc.identifier.cvuagro | 16261456 |
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