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Helicobacter pylori prevalence in healthy Mexican children: comparison between two non-invasive methods.
dc.contributor.author | Romero Castro, Norma Samanta | |
dc.contributor.author | Reyes Rios, Roxana | |
dc.contributor.author | Martinez Carrillo, Dinorah Nashely | |
dc.contributor.author | Fernández-Tilapa, Gloria | |
dc.contributor.author | Martínez-Santos, Verónica I. | |
dc.contributor.author | Manuel, Hernández Catalán | |
dc.contributor.author | Luis Octavio, Ojeda Salazar | |
dc.contributor.author | Orozco Gómez, Octavio Andrei | |
dc.contributor.author | Lorenzo, Sandra Ines | |
dc.contributor.author | Santos Gómez, Rayver | |
dc.creator | ROMERO CASTRO, NORMA SAMANTA; 358238 | |
dc.creator | REYES RIOS, ROXANA; 175116 | |
dc.creator | MARTINEZ CARRILLO, DINORAH NASHELY; 210671 | |
dc.creator | Fernández-Tilapa, Gloria;#0000-0002-3737-2399 | |
dc.date.accessioned | 2023-09-17T22:00:51Z | |
dc.date.available | 2023-09-17T22:00:51Z | |
dc.date.issued | 2021-06-28 | |
dc.identifier.issn | 10.7717/peerj.11546 | |
dc.identifier.uri | http://ri.uagro.mx/handle/uagro/3968 | |
dc.description.abstract | Background: Helicobacter pylori detection in asymptomatic children with suspected infection or with symptoms that suggest gastric pathology is problematic, since most of the methods depend on the endoscopic study, an invasive and expensive method. Non-invasive methods can be a feasible alternative but must be validated. The purpose of this study was to evaluate the concordance between H. pylori DNA detection in saliva and dental plaque by PCR, with antigen detection in stool by immunochromatography, among asymptomatic children in the state of Guerrero, Mexico. Methods: Dental plaque, saliva, and stool samples were obtained from 171 children between 6 and 12 years old. H. pylori detection in saliva and dental plaque was performed by PCR using specific primers for the 16S rRNA gene, while the detection in stool samples was performed by immunochromatography using the CerTest kit. Results: We found an overall H. pylori prevalence of 59.6% (102/171). Of the H. pylori positive children 18% (20/111) were positive in saliva samples, 28.1% (34/121) in dental plaque samples, and 50.4% (71/141) in stool samples. A higher prevalence was found in girls (64.7%, p = 0.002). Although some of the children declared some dyspeptic symptoms, these were no related to H. pylori. In conclusion, we found a high prevalence of H. pylori in asymptomatic children and the highest proportion was detected by stool antigen test, which was the most feasible method to detect H. pylori infection. | |
dc.format | ||
dc.language.iso | eng | |
dc.publisher | PeerJ, | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0 | |
dc.subject | H. pylori | |
dc.subject | Children | |
dc.subject | Non-invasive methods | |
dc.subject | Mexico | |
dc.subject | Prevalence | |
dc.subject.classification | MEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::OTRAS ESPECIALIDADES MÉDICAS::OTRAS | |
dc.title | Helicobacter pylori prevalence in healthy Mexican children: comparison between two non-invasive methods. | |
dc.type | Artículo | |
dc.type.conacyt | article | |
dc.rights.acces | openAccess | |
dc.audience | generalPublic | |
dc.identificator | 3||32||3299||329999 | |
dc.format.digitalOrigin | Born digital | |
dc.thesis.degreelevel | Especialidad | |
dc.thesis.degreename | Especialidad en Implantología y Rehabilitación Bucal | |
dc.thesis.degreegrantor | Universidad Autónoma de Guerrero | |
dc.thesis.degreedepartment | Facultad de Odontología | |
dc.thesis.degreediscipline | Medicina y Ciencias de la Salud | |
dc.identifier.cvuagro | 10908 |
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