• Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia. 

      Organista Nava, Jorge; Gomez Gomez, Yazmin; Illades_Aguiar, Berenice; Rivera Ramirez, Ana Bertha; Saavedra Herrera, Monica Virginia; Leyva Vazquez, Marco Antonio (ONCOLOGY LETTERS, 2017-08-23)
      Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted ...