• A possible association between the -2518 A>G MCP-1 polymorphism and insulin resistance in school children. 

      Matia Garcia, Ines; Salgado Goytia, Lorenzo; Ramos Arellano, Luz Elena; Muñoz_Valle, José Francisco; Armenta Solis, Adakatia; Garibay Cerdenares, Olga Lilia; Ramírez, Mónica; Parra_Rojas, Isela (SCIELO, 2017-08-09)
      Objective: Monocyte chemoattractant protein 1 (MCP-1) has been suggested to be involved in the pathophysiology of insulin resistance (IR); therefore, variants in the MCP-1 gene may contribute to the development of this ...
    • Association of extrapituitary prolactin promoter polymorphism with disease susceptibility and anti-RNP antibodies in Mexican patients with systemic lupus erythematosus. 

      Hernandez Bello, Jorge; Palafox Sanchez, Claudia Azucena; Garcia Arellano, Samuel; Reyes Castillo, Zyanya; Pereira Suarez, Ana Laura; Parra Rojas, Isela; Navarro Zarza, Jose Eduardo; De La Cruz Mosso, Ulises; Torres Carrillo, Nora Magdalena; Muñoz Valle, Jose Francisco (Archives of Medical Science, 2016-06-21)
      Prolactin (PRL) is a 23-kDa protein that can be synthesized and secreted by pituitary and extrapituitary tissues such as immune cells due to its expression being regulated by two independent promoter regions. The promoter ...
    • Efecto de HOTAIR sobre TET1 y la vía WNT en la línea celular HeLa. 

      Salmeron Barcenas, Eric Genaro (Universidad Autónoma de Guerrero (México), 2020-01)
      Hox transcript antisense intergenic RNA (HOTAIR) es un RNA no codificante largo (lncRNA) que se transcribe de la región 12q13.13, específicamente de la cadena antisentido en la región intergénica entre HOXC11 y HOXC12, y ...
    • Efecto de los antioxidantes sobre la expresión de moléculas que regulan la conducta alimentaria en ratas diabéticas. 

      Barragan Bonilla, Martha Isela (Universidad Autónoma de Guerrero (México), 2019-06)
      To establish a representative DM model that present most of the characteristics of the disease; and to evaluate if antioxidants can regulate diabetic hyperphagia and determine if this is related to the change in the ...
    • High relative abundance of firmicutes and increased TNF- ¿ levels correlate with obesity in children. 

      Orbe Orihuela, Yaneth Citlalli; Lagunas Martinez, Alfredo; Bahena Roman, Margarita; Madrid Marina, Vicente; Torres Poveda, Kirvis Janneth; Flores Alfaro, Eugenia; Méndez Padrón, Araceli; Diaz Benitez, Cinthya Estefhany; Peralta Zaragoza, Oscar; Antúnez Ortiz, Diana Lizzete; Cruz, Miguel; Burguete Garcia, Ana Isabel (Salud Pública de México, 2017-02-24)
      To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Materials and methods. Anthropometric data were obtained from 890 children under 14 years ...
    • Influence of serum leptin levels and Q223R leptin receptor polymorphism on clinical characteristic of patients with rheumatoid arthritis from Western Mexico. 

      Angel Chavez, Luis Ignacio; Ruelas Cinco, Elizabeth Del Carmen; Hernandez Bello, Jorge; Castro, Elena; Vazquez Villamar, Mirna; Parra_Rojas, Isela; Brennan Bourdon, Lorena Michele; Muñoz Barrios, Salvador; Guerrero Velazquez, Celia; Muñoz_Valle, José Francisco (eJIFCC, 2018-11)
      The aim of the present study was to evaluate the possible association between the Q223R Leptin receptor (LEPR) polymorphism (A>G; rs1137101) and leptin levels in patients with rheumatoid arthritis (RA) from Western Mexico.
    • MMP-2 salivary activity in type 2 diabetes mellitus patients 

      Arreguin Cano, Juan Antonio; Ayerdi Nájera, Brenda; Tacuba Saavedra, Arvey; Navarro Tito, Napoleon; Davalos Martinez, Alfonso; Emigdio Vargas, Abel; Barrera Rodriguez, Elia; Blanco García, Nubia; Gutierrez Venegas, Gloria; Ventura Molina, Elías; León Dorantes, Gladys (Diabetology & Metabolic Syndrome, 2019-01)
      Type 2 diabetes mellitus (T2DM) and periodontitis are chronic inflammatory diseases with a bidirec¿ tional relationship. The uncontrolled levels of glucose in T2DM patients change the pathophysiology and balance of ...
    • Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia. 

      Organista Nava, Jorge; Gomez Gomez, Yazmin; Illades_Aguiar, Berenice; Rivera Ramirez, Ana Bertha; Saavedra Herrera, Monica Virginia; Leyva Vazquez, Marco Antonio (ONCOLOGY LETTERS, 2017-08-23)
      Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted ...
    • PTPN22 1858C>T polymorphism is associated with increased CD154 expression and higher CD4+ T cells percentage in rheumatoid arthritis patients. 

      Ruiz Noa, Yeniley; Hernandez Bello, Jorge; Llamas Covarrubias, Mara Anais; Palafox Sanchez, Claudia Azucena; Oregon Romero, Edith; Sánchez Hernández, Pedro Ernesto; Ramirez Dueñas, Maria Guadalupe; Parra Rojas, Isela; Muñoz Valle, Jose Francisco (Journal Clinical Laboratory Analysis, 2018-10-14)
      Background: CD40 is a costimulatory molecule for B cells, and CD154 is a marker of CD4+ T cells activation. CD40 CD154 interaction promotes pro¿inflammatory cytokines secretion and autoantibodies production. PTPN22 gene ...
    • Resistencia a la insulina inducida por exposición a metamidofos: participación del estrés oxidativo. 

      Ramirez Vargas, Marco Antonio (Universidad Autónoma de Guerrero (México), 2018-01-01)
      induction of oxidative stress is a mechanism through which OP induces IR. The objective of this work was to evaluate whether MET is capable to generate IR in HepG2 cells. In addition, we investigated the relationship between ...