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Marcadores de disfunción endotelial asociados con riesgo cardiovascular en jóvenes con obesidad y peso normal
(Universidad Autónoma de Guerrero (México), 2013-10)
Obesity promotes endothelial dysfunction causing the detachment of endothelial cells and overexpression of cell adhesion molecules. Objective. To evaluate the ratio of the number of circulating endothelial cells and levels ...
Análisis proteómico en tejidos de cáncer epitelial de ovario de pacientes resistentes a la quimioterapia de primera línea
(Universidad Autónoma de Guerrero (México), 2013-10)
The agents of platinum and taxanes are the standard chemotherapy to treat ovarian epithelial cancer for more than 30 years, however, 70% of patients have resistance to these medications. In an effort to identify the cellular ...
Relación entre los grupos filogenéticos y factores de virulencia en Escherichia coli uropatógena en dos localidades en México
(Universidad Autónoma de Guerrero (México), 2014-10)
Uropathogenic Escherichia coli (UPEC) is the major causative agent of urinary tract infections (UTI) and virulence factors are responsible for the severity of these emerging infections. The aim of this study was to evaluate ...
Expresión de E-cadherina, SMA, Hic-5 y su correlación con el índice pronóstico Nottingham (IPN) en cáncer de mama
(Universidad Autónoma de Guerrero (México), 2018-11)
Breast cáncer (BrCa) is a heterogeneous disease that includes different molecular characteristics, behavior, morphological appearance and response to therapy. The routine clinical follow-up of patients with BrCa includes ...
Evaluación de la inmunogenicidad y efecto protector de la vacuna oral S3Pvac-papaya contra la cisticercosis en cerdos
(Universidad Autónoma de Guerrero (México), 2014-01)
Neurocysticercosis is a parasitic disease caused by the establishment of the larval stage of Taenia solium, which can be established in humans or pigs. Among the proposed control interventions include prevention of porcine ...
Análisis proteómico diferencial en suero de niños y adultos con y sin resistencia a insulina
(Universidad Autónoma de Guerrero (México), 2018-11)
Insulin resistance is a condition in which the target cells do not respond normally to the physiological actions of the hormone. Obesity and the consequent chronic inflammation of low grade have been associated with the ...
Haplotipos del gen SLC2A2 en población infantil con niveles de glucosa alterada en ayuno
(Universidad Autónoma de Guerrero (México), 2013-09)
Insulin secretion by pancreatic cells is stimulated by glucose, which is transported into the cell by GLUT2. Promoter region (rs5393, rs5394) and coding region (rs5400 and rs5404) polymorphism of SLC2A2 gene, encoding ...
Polimorfismos t786c, g894t y g10t en el gen NOS3 y su relación con presión arterial alta en población guerrerense
(Universidad Autónoma de Guerrero (México), 2017-01)
Globally, one in three adults has high blood pressure. Nitric oxide (NO) is an endogenous free radical, involved in vasorelaxation, and therefore, in reducing vascular resistance and blood pressure. Nitric oxide is synthesized ...
Participación de PI3K y Rac1 en la Transición Epitelio-Mesenquimal inducida por leptina en células MCF10A
(Universidad Autónoma de Guerrero (México), 2016-06)
Epithelial-Mesenchymal Transition (EMT) is associated with the acquisition of pro-metastatic properties in breast cancer cells. Deregulation in the production of adipocytokines, particularly overproduction of leptin, has ...
Efecto de la metilación de la LCR en la actividad transcripcional del VPH16
(Universidad Autónoma de Guerrero (México), 2015-01)
Experimental and epidemiological evidence suggests that CaCU is caused by persistent infection with high-risk HPV. Genotype 16 is the most commonly detected in CaCU. The E6 and E7 oncogenes largely explain the oncogenic ...