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Mostrando ítems 11-20 de 21
Perfil proteómico de exosomas secretados por macrófagos U937 DC-SIGN infectados con DENV-2 y efecto del contenido exosomal en la replicación viral.
(Universidad Autónoma de Guerrero (México), 2020-01)
Dengue is a disease caused by dengue virus. Dendritic cells, monocytes and macrophages, are mainly infected by this virus and these cells release exosomes during infection. Exosome secretion by cells infected by the DENV ...
Expresión de miR-26b, miR-100 y uno de sus genes blanco en células de leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2020-01)
MicroRNAs participate in the regulation of gene expression in multiple cellular processes, including leukemogenesis. miR-26b and miR-100 in acute lymphoblastic leukemia (ALL) have a deregulation in their expression. The ...
Efecto de E7 de referencia y de su variante C732/C789/G795 del VPH 16 sobre la expresión de las Isoformas de OCT4.
(Universidad Autónoma de Guerrero (México), 2019-12)
High-risk Human Papillomavirus (HPV-AR), such as HPV16, has been associated with the development of cervical cancer (CaCU). Several studies suggest that specific variations in the sequence of its oncogenes such as HPV E7 ...
Evaluación de la línea celular Huh7 como modelo de resistencia a la insulina determinado por diversos biomarcadores en comparación con HepG2.
(Universidad Autónoma de Guerrero (México), 2020-01)
Insulin resistance (RI) is defined as the inability of insulin to internalize glucose in its target cells, favoring the development of metabolic diseases. The liver plays an important role in the development of RI; hence, ...
Efecto de la metformina sobre marcadores bioquímicosmoleculares y secreción de exosomas en células HUH7 con resistencia a insulina.
(Universidad Autónoma de Guerrero (México), 2020-01)
Liver-specific insulin resistance is associated with the development of the main challenges in metabolism resulting in dyslipidemia, hyperinsulinemia and hyperglycemia. In vitro models developed for researching the hepatic ...
Expresión de HIF-1A y genes blanco in vitro e in silico en cáncer cervicouterino.
(Universidad Autónoma de Guerrero (México), 2022-12)
Cervical cancer (CC) is the most common cancer in women in the lower genital tract. The main risk factor for developing CC is persistent infection with HPV 16. The E6 and E7 oncoproteins of HPV 16 have been related to ...
Caracterización in silico y molecular del LncRNA MINCR y su posible papel en la migración en células C33-A/AA-c de E6 del VPH-16.
(Universidad Autónoma de Guerrero (México), 2021-12)
Infection with human papillomavirus 16 (HPV-16) is one of the first events in the carcinogenesis process in cervical cancer (CC). The expression of the viral oncoprotein E6 and E7 is essential in this process to inactivate ...
Análisis de la interacción de E6-prototipo de VPH-16 y sus variantes E6-AAa y E6-AAc con MAGI 1 y el efecto en su degradación.
(Universidad Autónoma de Guerrero (México), 2021-11-05)
Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) 18 mediates the degradation of Membrane-associated guanylate kinase with inverted 19 domain structure-1 (MAGI-1), throughout the interaction of its protein binding ...
Análisis de la expresión de marcadores de neuroprotección presentes en exosomas secretados por astrocitos hiperglucémicos.
(Universidad Autónoma de Guerrero (México), 2023-01)
Astrocytes are essential for the proper functioning of the nervous system. Various studies have shown that exosomes are essential for intercellular communication due to the content of various biomolecules that they can ...
Efecto del resveratrol sobre el estrés oxidante y la vía de señalización de la AMPK en hipotálamo de ratas Wistar con hiperglucemia.
(Universidad Autónoma de Guerrero (México), 2022-01)