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GTPasas RhoA, Rac1 y Cdc42 y los GEFs Tiam1 y BPix en el desarrollo de cáncer cervicouterino
(Universidad Autónoma de Guerrero (México), 2009-09)
Cervical cancer is an important health problem and one of the major causes of mortality in Mexico particularly in some states with high rates of exclusion, including the state of Guerrero. Fortunately, advances in molecular ...
Expresión de lumican, a-sma y ciclina D1 y su asociación con E6 del VPH de alto riesgo en lesiones premalignas y carcinoma cervical
(Universidad Autónoma de Guerrero (México), 2019-01)
The persistence and integration of HR-HPV, increase the risk of progression of squamous intraepithelial lesions (SIL) to invasive cervical carcinoma (CCI). The E6 protein of HR-HPV, plays an important role in cell ...
Efecto de la metilación de la LCR en la actividad transcripcional del VPH16
(Universidad Autónoma de Guerrero (México), 2015-01)
Experimental and epidemiological evidence suggests that CaCU is caused by persistent infection with high-risk HPV. Genotype 16 is the most commonly detected in CaCU. The E6 and E7 oncogenes largely explain the oncogenic ...
Evaluación de la expresión de peroxiredoxina III, MCM2/TOP2a y su relación con el estado físico del VPH-AR en la carcinogénesis cervical
(Universidad Autónoma de Guerrero (México), 2018-01)
Squamous cell carcinoma (SCC) is causally related to the high-risk human papilloma virus (HR-HPV) oncoproteins E6 and E7, several studies have suggested the role of oxidative stress in the progression of a squamous ...
Expresión de Cox-1 y Cox-2 en lesión escamosa intraepitelial de cérvix uterino e infección por el virus del papiloma humano
(Universidad Autónoma de Guerrero (México), 2011-01)
Background. Chronic inflammation plays an important role in HR-HPV associated cervical carcinogenesis. Recent studies show that HR-HPV infection activates proinflammatory enzymes such as cyclooxygenases (Cox-1 y Cox-2), ...