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HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells

dc.contributor.authorSalmeron Barcenas, Eric Genaro
dc.contributor.authorIllades_Aguiar, Berenice
dc.contributor.authorDel Moral Hernandez, Oscar
dc.contributor.authorOrtega Soto, Arturo
dc.contributor.authorHernandez Sotelo, Daniel
dc.creatorSALMERON BARCENAS, ERIC GENARO; 555413
dc.creatorIllades_Aguiar, Berenice;#0000-0003-3937-335X
dc.creatorDEL MORAL HERNANDEZ, OSCAR; 47380
dc.creatorORTEGA SOTO, ARTURO; 11534
dc.creatorHERNANDEZ SOTELO, DANIEL; 259435
dc.date.accessioned2020-04-03T01:19:54Z
dc.date.available2020-04-03T01:19:54Z
dc.date.issued2019-12-05
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1178
dc.description.abstractBackground/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some types of cancer. HOTAIR and TET1 are involved in modulation of the Wnt/ß-catenin signaling pathway, but their role in cervical cáncer remains to be elucidated.
dc.description.sponsorshipWe thank Juan Francisco Leyva-Illades for editing the manuscript. This study was supported by grant from CONACYT (242812), México.
dc.formatpdf
dc.language.isoeng
dc.publisherCellular Physiology and Biochemistry
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectWnt/ß-catenin
dc.subjectHOTAIR
dc.subjectMethylation
dc.subjectTET1 and hydroxymethylation
dc.subjectCellular Physiology
dc.subjectBiochemistry
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::OTRAS ESPECIALIDADES MÉDICAS
dc.titleHOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3299
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro12927


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