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Mostrando ítems 21-26 de 26
Análisis de la interacción de E6-prototipo de VPH-16 y sus variantes E6-AAa y E6-AAc con MAGI 1 y el efecto en su degradación.
(Universidad Autónoma de Guerrero (México), 2021-11-05)
Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) 18 mediates the degradation of Membrane-associated guanylate kinase with inverted 19 domain structure-1 (MAGI-1), throughout the interaction of its protein binding ...
Efecto de la expresión de la oncoproteína E6 de las variantes AA-a, E-G350 y E-A176/G350 del VPH-16 en la metilación de genes relacionados con adhesión, migración e invasión celular.
(Universidad Autónoma de Guerrero (México), 2021-07)
Several studies have shown that DNA hypermethylation is one of the main alterations that occur with greater frequency in the establishment of cervical carcinoma. The VPH E6 oncoprotein has already been shown to promote the ...
Análisis de la expresión de las isoformas de OCT4 y su significado clínico en leucemias agudas.
(Universidad Autónoma de Guerrero (México), 2021-07)
Introduction: Acute lymphoblastic leukemia (ALL) is characterized by the unregulated proliferation of B or T lymphoid precursor cells. Due to their ability to self-renewal, cancer stem cells (CSC) play a crucial role in ...
Efecto antioxidante sobre niveles plasmáticos de grelina/leptina y daño oxidativo hipotalámico en ratas con diabetes.
(Universidad Autónoma de Guerrero (México), 2021-07)
The hormones ghrelin and leptin are important signal regulators of energy homeostasis from the periphery to the hypothalamus. Diabetic hyperphagia is the result of the intracellular energy imbalance that leads to a state ...
Polimorfismos y haplotipos en el gen PADI2 y su relación con la diversificación clínica en pacientes con artritis reumatoide del sur de México.
(Universidad Autónoma de Guerrero (México), 2020-12)
Rheumatoid arthritis (RA) is a progressive autoimmune disease characterized by inflammation, pain, and joint limitation. The citrullination is a process mediated by peptidyl arginine deiminase (PADI) enzymes and is recognized ...
Análisis de la expresión de marcadores de neuroprotección presentes en exosomas secretados por astrocitos hiperglucémicos.
(Universidad Autónoma de Guerrero (México), 2023-01)
Astrocytes are essential for the proper functioning of the nervous system. Various studies have shown that exosomes are essential for intercellular communication due to the content of various biomolecules that they can ...