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dc.contributorVargas De Leon, Cruz
dc.contributorGodinez Jaimes, Flaviano
dc.contributor.advisorVARGAS DE LEON, CRUZ; 591497
dc.contributor.advisorGODINEZ JAIMES, FLAVIANO; 122953
dc.contributor.authorRodríguez Parra, Miguel Ángel
dc.date.accessioned2023-03-24T18:44:30Z
dc.date.available2023-03-24T18:44:30Z
dc.date.issued2021-11
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/3539
dc.description.abstractIn virology, mathematical models based on differential equations have been used to describe the dynamics of viral infections either with or without antiviral therapy and, based on this, are used as a tool to monitor replication inhibition viral and leading to cure of the infection or to keep the viral load below a threshold. In this work, Bayesian statistics are used to estimate the parameters of cell dynamics, viral dynamics, the efficacy of interferón (IFN), the basic reproductive number and other important parameters in viral infection models, from cell culture data. infected with Human Immunodeficiency Virus type 1 (HIV-1). Bayesian estimates of cell growth models and viral dynamics with or without interferon are presented, and the selection of the best model is made for each data set. The results obtained indicate that the inhibiting effects of interferon on viral replication and the production of new infections have the same efficacy. In addition, that interferon treatment significantly reduces the basic reproductive number and therefore the spread of the infection.
dc.formatpdf
dc.language.isospa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject.classificationCIENCIAS FÍSICO MATEMÁTICAS Y CIENCIAS DE LA TIERRA::MATEMÁTICAS::ESTADÍSTICA::ANÁLISIS DE DATOS
dc.titleEstimación Bayesiana de los parámetros de la eficacia del Interferón en una infección viral In Vitro.
dc.typeTesis de maestría
dc.type.conacytmasterThesis
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator1||12||1209||120903
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelMaestría
dc.thesis.degreenameMaestría en Matemáticas Aplicadas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Matemáticas
dc.thesis.degreedisciplineCiencias Físico Matemáticas y Ciencias de la Tierra
dc.identifier.cvuagro19370712


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