ListarArtículos Open Access por tema "leukemia"

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    • Association Between the 5,10-MTHFR 677C>T and RFC1 80G>A Polymorphisms and Acute Lymphoblastic Leukemia. 

      Gomez Gomez, Yazmin; Organista Nava, Jorge; Villanueva Flores, Fernando; Estrada Brito, José Silvestre; Rivera Ramirez, Ana Bertha; Saavedra Herrera, Monica Virginia; Jimenez Lopez, Marco Antonio; Leyva Vazquez, Marco Antonio; Illades_Aguiar, Berenice; Leyva Vazquez, Marco Antonio (ELSEVIER, 2019-05)
      Polymorphisms in folate-related genes are closely related to the development of cancer. The 5,10-MTHFR 677C>T and RFC1 80G>A polymorphisms are associated with an increased risk of susceptibility to pediatric ALL.

    • Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia. 

      Organista Nava, Jorge; Gomez Gomez, Yazmin; Illades_Aguiar, Berenice; Rivera Ramirez, Ana Bertha; Saavedra Herrera, Monica Virginia; Leyva Vazquez, Marco Antonio (ONCOLOGY LETTERS, 2017-08-23)
      Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted ...