Caracterización fitoquímica y actividad antiproliferativa de extractos de hoja de Ficus crocata en la línea celular MDA-MB-231

Abstract

Background: The Ficus genus comprises approximately 750 species of Moraceae family. Recent studies have been demonstrated that some species of this genus showed pharmacological activities, including antitumor activity. Ficus crocata is used in traditional medicine as anti-inflammatory, analgesic, antioxidant properties, however, there are no scientific reports on their biological activity. This study aims to evaluate the effect of extracts and fractions obtained from Ficus crocata leaves on the proliferation of MDA-MB-231 cells, and the possible mechanisms involved in the decrease of proliferation, as apoptosis and cell cycle arrest.