Buscar
Mostrando ítems 61-70 de 115
Haplotipos del gen SLC2A2 en población infantil con niveles de glucosa alterada en ayuno
(Universidad Autónoma de Guerrero (México), 2013-09)
Insulin secretion by pancreatic cells is stimulated by glucose, which is transported into the cell by GLUT2. Promoter region (rs5393, rs5394) and coding region (rs5400 and rs5404) polymorphism of SLC2A2 gene, encoding ...
Polimorfismos t786c, g894t y g10t en el gen NOS3 y su relación con presión arterial alta en población guerrerense
(Universidad Autónoma de Guerrero (México), 2017-01)
Globally, one in three adults has high blood pressure. Nitric oxide (NO) is an endogenous free radical, involved in vasorelaxation, and therefore, in reducing vascular resistance and blood pressure. Nitric oxide is synthesized ...
Participación de PI3K y Rac1 en la Transición Epitelio-Mesenquimal inducida por leptina en células MCF10A
(Universidad Autónoma de Guerrero (México), 2016-06)
Epithelial-Mesenchymal Transition (EMT) is associated with the acquisition of pro-metastatic properties in breast cancer cells. Deregulation in the production of adipocytokines, particularly overproduction of leptin, has ...
Efecto de la metilación de la LCR en la actividad transcripcional del VPH16
(Universidad Autónoma de Guerrero (México), 2015-01)
Experimental and epidemiological evidence suggests that CaCU is caused by persistent infection with high-risk HPV. Genotype 16 is the most commonly detected in CaCU. The E6 and E7 oncogenes largely explain the oncogenic ...
Polimorfismos en el gen PON1 y daño al DNA en población expuesta ocupacionalmente a plaguicidas organofosforados
(Universidad Autónoma de Guerrero (México), 2014-06)
PON1 is an enzyme that hydrolyzes the active metabolites of OP (oxons). It has determined that single nucleotide polymorphisms (SNP) in the promoter (108CT) and coding (L55M and Q192R) region of PON1 gene induce variations ...
Regulación de la expresión del receptor NMDA por el resveratrol en isquemia cerebral in vivo
(Universidad Autónoma de Guerrero (México), 2013-10)
Neuronal loss during cerebral ischemia can be prevented by modulating the celular redox state. It has been suggested that regulation of N-methyl-D-aspartate receptor subunits by antioxidants decrease glutamate excitotoxicity. ...
Polimorfismo -149C>T, expresión de la DNA metiltransferasa 3B y metilación de los promotores de los genes FHIT y MGMT en la carcinogénesis cervical
(Universidad Autónoma de Guerrero (México), 2010-12)
Infection with human papilloma virus (HPV) is necessary in the development of cervical cancer (CC), but clearly other factors that favor progression, and epigenetic alterations. Among them is DNA methylation is catalyzed ...
Papel de Src sobre marcadores clásicos de la transición epitelio-mesenquimal en células epiteliales mamarias estimuladas con leptina
(Universidad Autónoma de Guerrero (México), 2017-12)
Background: Several studies demonstrate an association between obesity and breast cancer (BC). Leptin is a hormone secreted by adipocytes which increases during obesity. Experimental evidence shown that leptin may promote ...
Efecto de la infección por Gardnerella vaginalis sobre la respuesta inmune innata en lesión escamosa intraepitelial de cérvix uterino y la línea celular HeLa
(Universidad Autónoma de Guerrero (México), 2018-11)
Bacterial vaginosis (BV) is a polymicrobial clinical entity characterized by the lack of inflammatory cells. However, in cervicovaginal fluids of women with BV, alterations in inflammatory cytokine levels have been reported ...
Modulación de la proliferación y supervivencia celular por la oncoproteína E6 de la variante E-G350 del VPH-16 en células HaCaT en respuesta a quimioterapia y radioterapia
(Universidad Autónoma de Guerrero (México), 2015-01)
E6 oncoprotein of HPV-16 alters cell proliferation, apoptosis, and the transcriptional regulation of several genes by binding to cellular proteins as E6AP, p53, Bax and caspase-8. Have been reported to E6 can bind and ...