HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells

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2019-12-05
Autor
Salmeron Barcenas, Eric Genaro
Illades_Aguiar, Berenice
Del Moral Hernandez, Oscar
Ortega Soto, Arturo
Hernandez Sotelo, Daniel
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Resumen
Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some types of cancer. HOTAIR and TET1 are involved in modulation of the Wnt/ß-catenin signaling pathway, but their role in cervical cáncer remains to be elucidated.
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http://ri.uagro.mx/handle/uagro/1178
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http://creativecommons.org/licenses/by-nc-nd/4.0
Excepto si se señala otra cosa, la licencia del ítem se describe como http://creativecommons.org/licenses/by-nc-nd/4.0