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vacA s1m1 genotype and cagA EPIYA-ABC pattern are predominant among Helicobacter pylori strains isolated from Mexican patients with chronic gastritis

dc.contributor.authorAtrisco Morales, Josefina
dc.contributor.authorMartinez Santos, Veronica Iranzu
dc.contributor.authorRoman Roman, Adolfo
dc.contributor.authorAlarcon Millan, Judit
dc.contributor.authorDe Sampedro Reyes, Jose
dc.contributor.authorCruz del Carmen, Ivan
dc.contributor.authorMartinez Carrillo, Dinorah Nashely
dc.contributor.authorFernandez Tilapa, Gloria
dc.creatorATRISCO MORALES, JOSEFINA; 628313
dc.creatorMARTINEZ SANTOS, VERONICA IRANZU; 166620
dc.creatorROMAN ROMAN, ADOLFO; 274958
dc.creatorALARCON MILLAN, JUDIT; 557685
dc.creatorMARTINEZ CARRILLO, DINORAH NASHELY; 210671
dc.creatorFERNANDEZ TILAPA, GLORIA; 90223
dc.date.accessioned2020-04-20T23:04:12Z
dc.date.available2020-04-20T23:04:12Z
dc.date.issued2017-11-30
dc.identifier.issnDOI 10.1099/jmm.0.000660
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1211
dc.descriptionHelicobacter pylori is a Gram-negative bacterium that colonizes the gastrointestinal tract of humans, mainly the gastric mucosa. These bacteria colonize around half of the world¿s population, although their prevalence varies among geographical regions within a country, as well as between rural and urban areas, due to the socio-economic conditions, age and population ethnicity [1, 2]. Even though 80% of the infected population is asymptomatic, persistent infection by these bacteria causes chronic inflammation of the mucosa, which manifests as gastritis that can develop to chronic atrophic gastritis, intestinal metaplasia, dysplasia, and finally, gastric cancer [3¿5].
dc.description.abstractPurpose. Virulent genotypes of Helicobacter pylori vacA s1m1/cagA+/babA2+ have been associated with severe gastric diseases. VacA, CagA and BabA are polymorphic proteins, and their association with the disease is allele-dependent. The aims of this work were: (i) to determine the prevalence of H. pylori by type of chronic gastritis; (ii) to describe the frequency of cagA, babA2 and vacA genotypes in strains from patients with different types of chronic gastritis; (iii) to characterize the variable region of cagA alleles.
dc.formatpdf
dc.language.isospa
dc.publisherMedical Microbiology
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::OTRAS ESPECIALIDADES MÉDICAS
dc.titlevacA s1m1 genotype and cagA EPIYA-ABC pattern are predominant among Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3299
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro18622


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