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Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells

dc.contributor.authorZacapala Gómez, Ana Elvira
dc.contributor.authorDel Moral Hernández, Oscar
dc.contributor.authorLeyva Vazquez, Marco Antonio
dc.contributor.authorIllades_Aguiar, Berenice
dc.contributor.authorAlarcón Romero, Luz Del Carmen
dc.contributor.authorHidalgo Miranda, Alfredo
dc.contributor.authorRomero Cordoba, Sandra Lorena
dc.contributor.authorBeltrán Anaya
dc.contributor.authorFredy Omar
dc.contributor.authorVillegas Sepúlveda, Nicolás
dc.creatorZacapala Gómez, Ana Elvira; 333917
dc.creatorDel Moral Hernández, Oscar; 47380
dc.creatorLeyva Vazquez, Marco Antonio; 264272
dc.creatorIllades_Aguiar, Berenice;#0000-0003-3937-335X
dc.creatorAlarcón Romero, Luz Del Carmen; 259901
dc.date.accessioned2019-04-04T00:02:02Z
dc.date.available2019-04-04T00:02:02Z
dc.date.issued2015-12-02
dc.identifier.issn0042-6822
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/404
dc.description.abstractWe analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned into an expression vector fused to GFP and was transfected in C33-Acells. Affymetrix GeneChip human Transcriptome Array 2.0 platform was used to analyze the expression of over 245,000 coding transcripts. We found that HPV16 E6 variant saltered the expression of 387 different genes in comparison withE-Prototype
dc.formatpdf
dc.language.isoeng
dc.publisherVirology
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4
dc.subjectCAB Thesaurus /Human papilloma virus
dc.subjectCAB Thesaurus /Oncoprotein variants
dc.subjectCAB Thesaurus /Cells global gene expression
dc.subjectCAB Thesaurus /Cervical carcinoma
dc.subject.classificationMEDICINA Y CIENCIAS DE LA SALUD::CIENCIAS MÉDICAS::PATOLOGÍA::CARCINOGÉNESIS
dc.titleChanges in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells
dc.typeArtículo
dc.type.conacytarticle
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator3||32||3207||320703
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelDoctorado
dc.thesis.degreenameDoctorado en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineMedicina y Ciencias de la Salud
dc.identifier.cvuagro12300135
dc.identifier.doihttp://dx.doi.org/10.1016/j.virol.2015.11.017


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4