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Efecto de la sobre-expresión de DNMT3B en la actividad transcripcional de genes relacionados con el cáncer
(Tlamati, 2017-06-30)Abnormal methylation of promoters of genes suppressors of tumor and repairers of DNA is an epigenetic process that leads to its transcriptional silencing and is also a common event observed in cancer. DNMT3B is a DNA ... -
Efecto de la sobreexpresión de miR-23b en los niveles de fosforilación de Gab1 y FAK vía c-Met y en la migración e invasión en líneas celulares de cáncer cervico uterino
(Universidad Autónoma de Guerrero (México), 2019-01)Cervical uterine cancer (CaCU) is the second most frequent cancer in women and persistent infection by HPV-AR is the main risk factor for its onset. Epigenetic factors such as the deregulated expression of microRNAs (miRNAs) ... -
Efecto de la sobreexpresión de miR-411-5p sobre el nivel de GRB2, la proliferación y migración en células AGS.
(Universidad Autónoma de Guerrero (México), 2021-07)Background: Dysregulation of microRNAs is associated with multiple human diseases, including cancer. Multiple studies have demonstrated the alteration of miR-411-5p and its duality of function in human cancer. Particularly ... -
Efecto de las variantes comunes en los genes SLC22A1 y SLC22A2 sobre el control glicémico de pacientes con diabetes tipo 2 tratados con metformina
(Universidad Autónoma de Guerrero (México), 2019-01)The organic cation transporters (OCT1 and OCT2) and the multidrug and toxin extrusiontransporter 1 (MATE1), encoded by the SLC22A1, SLC22A2, and SLC47A1 genes, respectively, are responsible for the absorption of the metformin ... -
Efecto De Las Variantes De La Oncoproteína E6 Del Vph 16 En La Adhesión Celular En Células C33-A
(Universidad Autónoma de Guerrero (México), 2019-01)To analyze the effect of HPV16 E6 oncoprotein variants E-G350, AA-a, AA-c, E-C188/G350 and E-A176/G350 in cell adhesion in C33-A cells. Methods: From cultures of C33-A cells transfected with HPV16 E6 gene of E-G350, AA-a, ... -
Efecto de las variantes de la oncoproteína E6 del VPH16 en la apoptosis inducida por cisplatino
(Universidad Autónoma de Guerrero (México), 2019-01)Several studies have been carried out that have analyzed the oncogenic potential of some variants of HPV16 and the deregulation of apoptosis. Demonstrating that the variants of the E6 oncoprotein of HPV16 and the E6 prototype ... -
Efecto de los antioxidantes sobre la expresión de moléculas que regulan la conducta alimentaria en ratas diabéticas.
(Universidad Autónoma de Guerrero (México), 2019-06)To establish a representative DM model that present most of the characteristics of the disease; and to evaluate if antioxidants can regulate diabetic hyperphagia and determine if this is related to the change in the ... -
Efecto de los taninos del fruto del cascalote (caesalpinia coriaria jacq. willd) sobre el comportamiento productivo, parámetros de fermentación ruminal, rendimiento y calidad de canal caprina
(Universidad Autónoma de Guerrero (México), 2018-06)Leaves and fruit of trees and shrubs containing secondary metabolites such as tannins are alternative resources for ruminants feeding. Secondary metabolites modified ruminal fermentation by inhibiting the ruminal NH3-N and ... -
Efecto de miR-24 sobre YKL-40 en leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2021-01)YKL-40 also known as CHI3L1 (Chitinase-3-like protein 1), is an inflammatory glycoprotein which is secreted by different cell types such as inflammatory cells. This protein is elevated in the serum or plasma of patients ... -
Efecto de una estrategia de capacitación para la prevención de infecciones de vías urinarias del Hospital General de Acapulco 2017
(Universidad Autónoma de Guerrero (México), 2018-01)Long-term urinary catheters are the leading cause of morbidity in intensive care settings, accounting for up to 40% of hospital-associated infections. The case-fatality rate of bacteremia associated with urinary tract ... -
Efecto del CdCl2 sobre la expresión de DNA metiltransferasas y la metilación de los genes RASSF1A, MGMT y SOX17 en células HepG2
(Universidad Autónoma de Guerrero (México), 2019-03)Cadmium (Cd) is a highly toxic heavy metal, established as carcinogen. There is evidence of Cd mediated epigenetic modifications, such as changes in methylation, resulting in alteration in target gene expression. This could ... -
Efecto del extracto de ajo envejecido sobre el nivel de especies reactivas de oxígeno y fosforilación de la AMPK en un modelo in vivo de diabetes
(Universidad Autónoma de Guerrero (México), 2017-01)Hyperglycemia in diabetes is associated with long-term damage and dysfunction of organs such as eyes, kidney and heart. Hyperglycemia generates an increase in the production of reactive oxygen species and a decrease in ... -
Efecto del extracto de ajo envejecido y Salilcisteina en la regulación de Erk 1/2 y Akt en un modelo de Isquemia cerebral in vivo
(Universidad Autónoma de Guerrero (México), 2011-01) -
Efecto del resveratrol en la fosforilación de AMPK en isquemia cerebral
(Tlamati, 2016-12)Cerebral ischemia results from occlusion of an important cerebral artery. Decreased cerebral blood flow restricts the supply of oxygen and glucose by lowering the energetic metabolism of the cell. Neuronal loss can be ... -
Efecto del resveratrol sobre el estrés oxidante y la vía de señalización de la AMPK en hipotálamo de ratas Wistar con hiperglucemia.
(Universidad Autónoma de Guerrero (México), 2022-01) -
Efecto del resveratrol sobre el nivel de expresión de los transportadores de glucosa GLUT en isquemia cerebral in vivo
(Universidad Autónoma de Guerrero (México), 2014-01)Ischemic stroke results from occlusion of a major cerebral artery and involves a cascade of metabolic events that begin during insult and proceed well into the blood flow recovery period [reperfusion (R)]. Impairment of ... -
Efecto del resveratrol sobre el nivel de expresión de los transportadores de glucosa GLUTs en isquemia cerebral in vivo
(Tlamati, 2017-06)Ischemia results from the occlusion of an important cerebral artery, generating cellular metabolic alterations, which is exacerbated during reperfusion. Decrease in cerebral blood flow restricts delivery of oxygen and ... -
Efecto del resveratrol sobre la activación de AMPK y el nivel de especies reactivas de oxígeno en un modelo in vivo de isquemia cerebral
(Universidad Autónoma de Guerrero (México), 2015-02)Cerebral ischemia results from occlusion of a major cerebral artery. Decreased cerebral blood flow restricts the supply of oxygen and glucose decreasing energy metabolism of the cell and increasing the level of reactive ... -
Efecto del resveratrol sobre la actividad de unión de los factores de transcripción Sp y NRF1 en un modelo in vivo de isquemia cerebral
(Universidad Autónoma de Guerrero (México), 2015-02)Cerebral ischemia results from decreased blood flow due to obstruction or thrombosis of a major cerebral artery. This event can trigger cell death or cell survival pathways depending on various factors such as the concentration ... -
Efecto del resveratrol sobre la hiperfagia y la expresión del receptor de grelina (GHSR-1a) en núcleo arcuato de ratas diabéticas.
(Universidad Autónoma de Guerrero (México), 2020-01)Hyperphagia is a classic manifestation in diabetes mellitus (DM), although there are first-line drugs that improve various symptoms of the disease, there is currently no medication capable of controlling hyperphagic behavior. ...