• Analysis of admixture proportions in seven geographical regions of the state of Guerrero, Mexico. 

      Cahua Pablo, Jose Angel; Cruz, Miguel; Tello Almaguer, Pedro Vidal; Alarcón Romero, Luz Del Carmen; Juan Parra, Esteban; Villerias Salinas, Salvador; Valladares Salgado, Adan; Tello Flores, Vianet Argelia; Mendez Palacios, Abigail; Perez Macedonio, Claudia Paola; Flores_Alfaro, Eugenia (WILEY, 2017-01)
      Mexico¿s current population structure has been defined by admixture between European, Native American, and to some extent African, groups that started in thesixteenth century. The aim of this research was toanalyze the ...
    • Association of human papillomavirus 16 E6 variants with cervical carcinoma and precursor lesions in women from Southern Mexico 

      Ortiz Ortiz, Julio; Alarcón Romero, Luz Del Carmen; Jiménez López, Marco Antonio; Leyva Vazquez, Marco Antonio; Illades_Aguiar, Berenice (Virology Journal, 2015-02-22)
      HPV 16 is the cause of cervical carcinoma, but only a small fraction of women with HPV infection progress to this pathology. Besides persistent infection and HPV integration, several studies have suggested that HPV intratype ...
    • Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells 

      Zacapala Gómez, Ana Elvira; Del Moral Hernández, Oscar; Leyva Vazquez, Marco Antonio; Illades_Aguiar, Berenice; Alarcón Romero, Luz Del Carmen; Hidalgo Miranda, Alfredo; Romero Cordoba, Sandra Lorena; Beltrán Anaya; Fredy Omar; Villegas Sepúlveda, Nicolás (Virology, 2015-12-02)
      We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned ...
    • Differential proteins among normal cérvix cells and cervical cancer cells with HPV-16 infection, through mass spectrometrybased Proteomics (2D-DIGE) in women from Southern México 

      Serafín Higuera, Idanya Rubí; Garibay Cerdenares, Olga Lilia; Illades_Aguiar, Berenice; Flores Alfaro, Eugenia; Jiménez López, Marco Antonio; Sierra Martínez, Pavel; Alarcón Romero, Luz Del Carmen (Proteome Science, 2016-09-05)
      Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are several diagnosis ...
    • Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions 

      Torres Rojas, Francisco Israel; Alarcón Romero, Luz Del Carmen; Leyva Vazquez, Marco Antonio; Ortiz Ortiz, Julio; Mendoza Catalán, Miguel Ángel; Hernández Sotelo, Daniel; Del Moral Hernández, Oscar; Rodríguez Ruiz, Hugo Alberto; Leyva Illades, Dinorah; Flores Alfaro, Eugenia; Illades_Aguiar, Berenice (Oncology Letters, 2017-09-13)
      High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ...
    • MicroRNA miR-16-1 regulates CCNE1 (cyclin E1) gene expression in human cervical cancer cells 

      Zubillaga Guerrero, Ma. Isabel; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Flores Alfaro, Eugenia; Peralta Zaragoza, Oscar (International Journal of Clinical and Experimental Medicine, 2015-09-30)
      MicroRNAs are involved in diverse biological processes through regulation of gene expression. The microRNA profile has been shown to be altered in cervical cancer (CC). MiR-16-1 belongs to the miR-16 cluster and has been ...
    • miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer 

      Campos Viguri, Gabriela Elizabeth; Jiménez Wences, Hilda; Torres Altamirano, Gricenda; Hernández Sotelo, Daniel; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Fernandez Tilapa, Gloria (Infectious Agents and Cancer, 2015-01)
      The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ...
    • Nuclear expression of Rac1 in cervical premalignant lesions and cervical cáncer cells 

      Mendoza Catalán, Miguel Ángel; Cristóbal Mondragón, Gema Rosa; Del Valle Flores, Heidi Nayeli; Romero Hernández, Mirna Azalea; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Castañeda Saucedo, Eduardo (BMC Cancer, 2012-03-23)
      Abnormal expression of Rho-GTPases has been reported in several human cancers. However, the expression of these proteins in cervical cancer has been poorly investigated. In this study we analyzed the expression of the ...
    • Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México 

      Cahua Pablo, Jose Angel; Méndez Palacios, Abigael; Antúnez Ortiz, Diana Lizzete; Vences Velázquez, Amalia; Alarcón Romero, Luz Del Carmen; Tello Flores, Vianet Argelia; Leyva Vazquez, Marco Antonio; Pérez Macedonio, Claudia Paola; Flores Alfaro, Eugenia (International Journal of Molecular Sciences, 2015-09-08)
      Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ...
    • Risk of progression of early cervical lesions is associated with Integration and persistence of HPV-16 and expression of E6, Ki-67, and telomerase) 

      Vega Peña, Arianna; Illades_Aguiar, Berenice; Flores Alfaro, Eugenia; Leyva Vazquez, Marco Antonio; Castañeda Saucedo, Eduardo; Alarcón Romero, Luz Del Carmen (2015-09-04)
      Low-grade squamous intraepithelial lesions (LSIL) are the earliest lesions of the uterine cervix, the persistence and integration of high-risk human papillomavirus (HR-HPV) as type 16, which promotes the development of ...