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Adenovirus 36 y su relación con obesidad y perfil metabólico en población adulta del Estado de Guerrero
(Universidad Autónoma de Guerrero (México), 2017-12)
Obesity is a chronic disease caused mainly by a sedentary lifestyle, poor eating habits and genetics; which is characterized by an increase in the mass of adipose tissue as a result of the excessive accumulation of fat in ...
Efecto del extracto de ajo envejecido sobre el nivel de especies reactivas de oxígeno y fosforilación de la AMPK en un modelo in vivo de diabetes
(Universidad Autónoma de Guerrero (México), 2017-01)
Hyperglycemia in diabetes is associated with long-term damage and dysfunction of organs such as eyes, kidney and heart. Hyperglycemia generates an increase in the production of reactive oxygen species and a decrease in ...
Metilación del gen l1 del VPH-16 como marcador de cáncer cervical
(Tlamati, 2017-06-30)
A total of 14 infection-positive samples were processed only for HPV-16, of which 5 were cytologically diagnosed as normal cytology (CN), 6 as a low-grade squamous intraepithelial lesion (LEIBG) and 3 cancer samples. The ...
Efecto de la sobre-expresión de DNMT3B en la actividad transcripcional de genes relacionados con el cáncer
(Tlamati, 2017-06-30)
Abnormal methylation of promoters of genes suppressors of tumor and repairers of DNA is an epigenetic process that leads to its transcriptional silencing and is also a common event observed in cancer. DNMT3B is a DNA ...
Interacción del consumo de sal con polimorfismos en el canal epitelial de sodio y su relación con presión arterial alta en población guerrerense
(Universidad Autónoma de Guerrero (México), 2017-01)
Prehypertension is a complex disease where genetic and environmental factors interact. Excessive consumption of sodium is one of the environmental factors that alters blood pressure. The sodium channel epithelial (ENaC) ...
Interacción de la dieta con la microbiota intestinal y su relación con el perfil metabólico en jóvenes con obesidad y normopeso
(Universidad Autónoma de Guerrero (México), 2017-01)
Background: The gut microbiota is considered to be an "organ", because it meets host's structural functions, it contributes in the development of the immune system and metabolism. It has been found that bacteria in the gut ...
Estudio de variantes del número de copias en genes candidato asociados a obesidad infantil
(Universidad Autónoma de Guerrero (México), 2017-02)
Obesity is one of the major health problems in the world, in Mexico the combined prevalence of overweight and obesity in school-age children is 34.4%. The weight gain starts during childhood, in its origin, environmental ...
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
(American Journal of Cancer Research, 2017-01)
Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ...
Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions
(Oncology Letters, 2017-09-13)
High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ...
Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
(Clin Exp Pathol, 2017-10-15)
Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ...