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RNAs largos no codificantes (lncRNAs) y su relación con diabetes tipo 2
(Universidad Autónoma de Guerrero (México), 2019-01)
Type-2 diabetes (T2D) has been linked to different environmental, genetic and epigenetic factors. It has been described that the expression of H19, MALAT1 and MIAT is related to metabolic diseases such as metabolic syndrome, ...
Marcadores de disfunción endotelial asociados con riesgo cardiovascular en jóvenes con obesidad y peso normal
(Universidad Autónoma de Guerrero (México), 2013-10)
Obesity promotes endothelial dysfunction causing the detachment of endothelial cells and overexpression of cell adhesion molecules. Objective. To evaluate the ratio of the number of circulating endothelial cells and levels ...
Análisis proteómico en tejidos de cáncer epitelial de ovario de pacientes resistentes a la quimioterapia de primera línea
(Universidad Autónoma de Guerrero (México), 2013-10)
The agents of platinum and taxanes are the standard chemotherapy to treat ovarian epithelial cancer for more than 30 years, however, 70% of patients have resistance to these medications. In an effort to identify the cellular ...
Relación entre los grupos filogenéticos y factores de virulencia en Escherichia coli uropatógena en dos localidades en México
(Universidad Autónoma de Guerrero (México), 2014-10)
Uropathogenic Escherichia coli (UPEC) is the major causative agent of urinary tract infections (UTI) and virulence factors are responsible for the severity of these emerging infections. The aim of this study was to evaluate ...
Expresión de E-cadherina, SMA, Hic-5 y su correlación con el índice pronóstico Nottingham (IPN) en cáncer de mama
(Universidad Autónoma de Guerrero (México), 2018-11)
Breast cáncer (BrCa) is a heterogeneous disease that includes different molecular characteristics, behavior, morphological appearance and response to therapy. The routine clinical follow-up of patients with BrCa includes ...
Evaluación de la inmunogenicidad y efecto protector de la vacuna oral S3Pvac-papaya contra la cisticercosis en cerdos
(Universidad Autónoma de Guerrero (México), 2014-01)
Neurocysticercosis is a parasitic disease caused by the establishment of the larval stage of Taenia solium, which can be established in humans or pigs. Among the proposed control interventions include prevention of porcine ...
Polimorfismo G80A del acarreador de folatos reducidos y respuesta a Metotrexato en Leucemia aguda linfoblástica
(Universidad Autónoma de Guerrero (México), 2009-12)
Leukemia is a hematological desorder who is characterized by uncontrolled proliferation of leukocytes in the bone marrow and peripheral blood, depending upon the celular type affected. Leukemias are classified in acute ...
Polimorfismos en el gen de la Dihidrofolato Reductasa y respuesta al Metotrexato en Leucemia Linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)
The presence of polymorphisms in regulatory regions causes increased expression of dihydrofolate reductase (DHFR), and it is associated with methotrexate (MTX) treatment adverse events. A case control study was conducted ...
Participación de PI3K y Rac1 en la Transición Epitelio-Mesenquimal inducida por leptina en células MCF10A
(Universidad Autónoma de Guerrero (México), 2016-06)
Epithelial-Mesenchymal Transition (EMT) is associated with the acquisition of pro-metastatic properties in breast cancer cells. Deregulation in the production of adipocytokines, particularly overproduction of leptin, has ...
Efecto de la metilación de la LCR en la actividad transcripcional del VPH16
(Universidad Autónoma de Guerrero (México), 2015-01)
Experimental and epidemiological evidence suggests that CaCU is caused by persistent infection with high-risk HPV. Genotype 16 is the most commonly detected in CaCU. The E6 and E7 oncogenes largely explain the oncogenic ...