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HOTAIR Knockdown Decreased the Activity Wnt/ß-Catenin Signaling Pathway and Increased the mRNA Levels of Its Negative Regulators in Hela Cells
(Cellular Physiology and Biochemistry, 2019-12-05)
Background/Aims: HOTAIR is a long non-coding RNA that promotes the development of human cancer. TET1 enzyme is involved in DNA demethylation by oxidation of 5-methylcytocine and it is considered a tumor suppressor in some ...
miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer
(Infectious Agents and Cancer, 2015-01)
The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ...
Differential proteins among normal cérvix cells and cervical cancer cells with HPV-16 infection, through mass spectrometrybased Proteomics (2D-DIGE) in women from Southern México
(Proteome Science, 2016-09-05)
Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are several diagnosis ...
CagL polymorphisms D58/K59 are predominant in Helicobacter pylori strains isolated from Mexican patients with chronic gastritis.
(Gut Pathogens, 2019-02-13)
Helicobacter pylori is a Gram¿negative bacterium that colonizes the gastric mucosa in humans. One of the main virulence factors of H. pylori is the cag pathogenicity island (cagPAI), which encodes a type 4¿secretion system ...
Niveles de expresión, metilación y polimorfismos en el gen de leptina en madres-neonatos como determinantes del peso al nacer
(Universidad Autónoma de Guerrero (México), 2015-10)
Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells
(Clin Exp Pathol, 2017-10-15)
Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ...
Relación entre polimorfismos en el gen ESR1 y el origen ancestral amerindio con síndrome metabólico y riesgo a enfermedad coronaria cardíaca
(Universidad Autónoma de Guerrero (México), 2015-07)
Changes in global gene expression profiles induced by HPV16 E6 oncoprote invariants incervical carcinoma C33-Acells
(Virology, 2015-12-02)
We analyzed the effects of the expression of HPV 16 E6 oncoprotein variants (AA-a, AA-c, E-A176/G350, E-C188/G350, E-G350), and the E-Prototype in global gene expression profiles in an in vitro model. E6 gene was cloned ...
Efecto de miR-24 sobre YKL-40 en leucemia linfoblástica aguda.
(Universidad Autónoma de Guerrero (México), 2021-01)
YKL-40 also known as CHI3L1 (Chitinase-3-like protein 1), is an inflammatory glycoprotein which is secreted by different cell types such as inflammatory cells. This protein is elevated in the serum or plasma of patients ...
Metilación del gen l1 del VPH-16 como marcador de cáncer cervical
(Tlamati, 2017-06-30)
A total of 14 infection-positive samples were processed only for HPV-16, of which 5 were cytologically diagnosed as normal cytology (CN), 6 as a low-grade squamous intraepithelial lesion (LEIBG) and 3 cancer samples. The ...