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Análisis de metilación del ADN de VPH 16 integrado al genoma celular
(Universidad Autónoma de Guerrero (México), 2009-01)
Background. Loss of gene expression regulation is a key characteristic of cancer; epigenetic modifications alter gene expression and thus play an important role in carcinogenesis. Integration of viral DNA in persistent ...
Polimorfismo G80A del acarreador de folatos reducidos y respuesta a Metotrexato en Leucemia aguda linfoblástica
(Universidad Autónoma de Guerrero (México), 2009-12)
Leukemia is a hematological desorder who is characterized by uncontrolled proliferation of leukocytes in the bone marrow and peripheral blood, depending upon the celular type affected. Leukemias are classified in acute ...
Polimorfismos en el gen de la Dihidrofolato Reductasa y respuesta al Metotrexato en Leucemia Linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)
The presence of polymorphisms in regulatory regions causes increased expression of dihydrofolate reductase (DHFR), and it is associated with methotrexate (MTX) treatment adverse events. A case control study was conducted ...
Helicobacter pylori y polimorfismos 511 ct y 31tc de la il-1b en pacientes con gastritis crónica y úlcera gástrica
(Universidad Autónoma de Guerrero (México), 2009-01)
The genotype vacA s1m1 of H. pylori is associate with the inflammation induction and damage in the gastric mucosa. In people with the polymorphisms 511 CT and -31 TC the IL1B the infection with this genotype of Helicobacter ...
Polimorfismo 62 GA en la región 3UTR del gen retn y niveles sanguíneos de la resistina en pacientes con diabetes tipo 2
(Universidad Autónoma de Guerrero (México), 2009-06)
Resistin is a proteic hormone secreted mainly by adipose tissue. It has been suggested a possible role of the resistin in the glucose metabolism. In mouse models, resistin overexpression produce a diminished sensitivity ...
Análisis proteómico del intestino del mosquito Aedes aegypti durante la hematofagia
(Universidad Autónoma de Guerrero (México), 2009-01)
The purpose of this study was to identify proteins from the midgut of Ae. aegypti, whose expression is changed by the hematophagy and others that are constituents of cell membranes. Materials and methods. Midguts of ...
Polimorfismos de la dnmt3b y su asociación con el desarrollo de lesiones precancerosas y cáncer cérvico uterino
(Universidad Autónoma de Guerrero (México), 2009-06)
Epigenetic and genetic factors are important for the development of cervical cancer (CC). DNMT3B plays a crucial role in carcinogenesis, its novo metilase activity can lead to silencing of tumor suppressor genes. Polymorphic ...
Expresion de telomerasa, KI-67 y el Virus del Papiloma Humano oncogénico en neoplasias intraepiteliales cervicales
(Universidad Autónoma de Guerrero (México), 2009-10)
Evaluate the relationship between Ki-67 and telomerase expression with CIN grade and the physical state of high risk human papillomavirus (HR-HPV) DNA. Methods. An observational comparative study was done of 80 fragments ...
Expresión de COX-2, MMP-9 y VEGF en lesiones premalignas de cérvix uterino e infección por el virus del papiloma humano
(Universidad Autónoma de Guerrero (México), 2009-11)
Low-grade (LSIL) and high-grade (HSIL) squamous intraepithelial lesions represent premalignant stages of cervical cancer. Cervical cancer represents the first cause of cancer-associated deaths among Mexican women. Chronic ...
GTPasas RhoA, Rac1 y Cdc42 y los GEFs Tiam1 y BPix en el desarrollo de cáncer cervicouterino
(Universidad Autónoma de Guerrero (México), 2009-09)
Cervical cancer is an important health problem and one of the major causes of mortality in Mexico particularly in some states with high rates of exclusion, including the state of Guerrero. Fortunately, advances in molecular ...