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Tumor suppressor miR-29c regulates radioresistance in lung cancer cells
(Tumor Biology, 2017-03)
Radiotherapy is an important treatment option for non-small cell lung carcinoma patients. Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of cancer cells that limits the efficacy of ...
vacA s1m1 genotype and cagA EPIYA-ABC pattern are predominant among Helicobacter pylori strains isolated from Mexican patients with chronic gastritis
(Medical Microbiology, 2017-11-30)
Purpose. Virulent genotypes of Helicobacter pylori vacA s1m1/cagA+/babA2+ have been associated with severe gastric diseases. VacA, CagA and BabA are polymorphic proteins, and their association with the disease is ...
The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo
(BioMed Research International, 2017-10-10)
High relative abundance of firmicutes and increased TNF- ¿ levels correlate with obesity in children.
(Salud Pública de México, 2017-02-24)
To investigate the correlation among pro- or anti-inflammatory cytokines and the two main gut microbiota phyla in obese children. Materials and methods. Anthropometric data were obtained from 890 children under 14 years ...
Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia.
(ONCOLOGY LETTERS, 2017-08-23)
Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted ...
Metilación del gen L1 e integración de VPH-AR en citología normal, lesiones precancerosas y CaCU y efecto de E6 en la metilación de genes relacionados a cáncer
(Universidad Autónoma de Guerrero (México), 2017-01)
Cervical cancer (CaCU) is the third most common neoplasm among women, whose causative agent is the human papillomavirus (HPV). HPV 16 and 18 are most frequently associated with this malignancy. Viral integration is a ...
Estudio de variantes del número de copias en genes candidato asociados a obesidad infantil
(Universidad Autónoma de Guerrero (México), 2017-02)
Obesity is one of the major health problems in the world, in Mexico the combined prevalence of overweight and obesity in school-age children is 34.4%. The weight gain starts during childhood, in its origin, environmental ...
Análisis de marcadores de la transición epiteliomesénquima en células de epitelio mamario no tumoral en respuesta a leptina.
(Universidad Autónoma de Guerrero (México), 2017-10)
A possible association between the -2518 A>G MCP-1 polymorphism and insulin resistance in school children.
(SCIELO, 2017-08-09)
Objective: Monocyte chemoattractant protein 1 (MCP-1) has been suggested to be involved in the pathophysiology of insulin resistance (IR); therefore, variants in the MCP-1 gene may contribute to the development of this ...
DNMT3B modulates the expression of cancer-related genes and downregulates the expression of the gene VAV3 via methylation
(American Journal of Cancer Research, 2017-01)
Altered promoter DNA methylation is one of the most important epigenetic abnormalities in human cancer. DNMT3B, de novo methyltransferase, is clearly related to abnormal methylation of tumour suppressor genes, DNA repair ...