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dc.contributorHernandez Sotelo, Daniel
dc.contributor.advisorHERNANDEZ SOTELO, DANIEL; 259435
dc.contributor.authorGomez Sonora, Jessica Paola
dc.creatorGOMEZ SONORA, JESSICA PAOLA; 857779
dc.date.accessioned2020-07-08T17:34:39Z
dc.date.available2020-07-08T17:34:39Z
dc.date.issued2020-01
dc.identifier.urihttp://ri.uagro.mx/handle/uagro/1556
dc.description.abstractThe lncRNA HOTAIR regulates gene expression through DNA methylation. HOTAIR is overexpressed in cervical cancer and modulates migration, invasion, proliferation, and apoptosis among other cellular processes. The migration and cellular invasion events in tumoral cells are enhanced by changes in the expression profile of adhesion molecules, which promotes alterations in the interaction dynamics between tumoral cells-extracellular matrix (ECM) and tumoral cells-other cells.
dc.formatpdf
dc.language.isospa
dc.publisherUniversidad Autónoma de Guerrero (México)
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0
dc.subjectHOTAIR
dc.subjectDNA methylation
dc.subjectcellular adhesion molecules
dc.subjectEZH2
dc.subjectcervical cancer
dc.subject.classificationBIOLOGÍA Y QUÍMICA::QUÍMICA::BIOQUÍMICA
dc.titleEfecto de la disminución de HOTAIR en la metilación y expresión de los genes CDH3, ITGA8, HLA-DRA y VCAM1, que participan en adhesión celular, en la línea celular HeLa.
dc.typeTesis de maestría
dc.contributor.committeeMemberCerdenares, Lilia Garibay
dc.contributor.committeeMemberDel Moral Hernández, Oscar
dc.contributor.committeeMemberCastañeda Saucedo, Eduardo
dc.contributor.committeeMemberHidalgo Miranda, Alfredo
dc.type.conacytmasterThesis
dc.rights.accesopenAccess
dc.audiencegeneralPublic
dc.identificator2||23||2302
dc.format.digitalOriginBorn digital
dc.thesis.degreelevelMaestría
dc.thesis.degreenameMaestría en Ciencias Biomédicas
dc.thesis.degreegrantorUniversidad Autónoma de Guerrero
dc.thesis.degreedepartmentFacultad de Ciencias Químico Biológicas
dc.thesis.degreedisciplineBiología y Química
dc.identifier.cvuagro12337270


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by-nc-nd/4.0