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GTPasas RhoA, Rac1 y Cdc42 y los GEFs Tiam1 y BPix en el desarrollo de cáncer cervicouterino
(Universidad Autónoma de Guerrero (México), 2009-09)
Cervical cancer is an important health problem and one of the major causes of mortality in Mexico particularly in some states with high rates of exclusion, including the state of Guerrero. Fortunately, advances in molecular ...
Polimorfismos +1444 c/t y +1846 g/a del gen de la proteína C reactiva y su asociación con los niveles de su proteína en personas con obesidad
(Universidad Autónoma de Guerrero (México), 2009-08)
Several single nucleotide polymorphisms (SNPs) in the C reactive protein gene (CRP) have been associated with increase serum concentration of their protein, some of them have been correlated with cardiovascular disease. ...
Polimorfismos A19G en el gen de leptina y A668G en su receptor y su relación con las concentraciones de leptina sérica y la hiperfagia en niños con obesidad
(Universidad Autónoma de Guerrero (México), 2009-09)
Leptin is an anorexigenic hormone that controls food intake and energy homeostasis, which by binding to its receptors in the hypothalamus, releases signals that generates a feeling of satiety, regulating appetite and weight ...
Participación de mTOR en la regulación del transportador EAAC1 en células C6 de Glioma
(Universidad Autónoma de Guerrero (México), 2009-08)
Glutamate (Glu) is the major excitatory neurotransmitter in the vertebrate central nervous system (CNS); it is involved in neural plasticity as well in learning and memory. Neuronal and glial sodium-dependent transporters ...
Expresión de COX-2, MMP-9 y VEGF en lesiones premalignas de cérvix uterino e infección por el virus del papiloma humano
(Universidad Autónoma de Guerrero (México), 2009-11)
Low-grade (LSIL) and high-grade (HSIL) squamous intraepithelial lesions represent premalignant stages of cervical cancer. Cervical cancer represents the first cause of cancer-associated deaths among Mexican women. Chronic ...
Polimorfismo G80A del acarreador de folatos reducidos y respuesta a Metotrexato en Leucemia aguda linfoblástica
(Universidad Autónoma de Guerrero (México), 2009-12)
Leukemia is a hematological desorder who is characterized by uncontrolled proliferation of leukocytes in the bone marrow and peripheral blood, depending upon the celular type affected. Leukemias are classified in acute ...
Polimorfismos en el gen de la Dihidrofolato Reductasa y respuesta al Metotrexato en Leucemia Linfoblástica aguda en México
(Universidad Autónoma de Guerrero (México), 2009-08)
The presence of polymorphisms in regulatory regions causes increased expression of dihydrofolate reductase (DHFR), and it is associated with methotrexate (MTX) treatment adverse events. A case control study was conducted ...
Análisis de metilación del ADN de VPH 16 integrado al genoma celular
(Universidad Autónoma de Guerrero (México), 2009-01)
Background. Loss of gene expression regulation is a key characteristic of cancer; epigenetic modifications alter gene expression and thus play an important role in carcinogenesis. Integration of viral DNA in persistent ...