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Now showing items 11-20 of 23
Evaluación de la línea celular Huh7 como modelo de resistencia a la insulina determinado por diversos biomarcadores en comparación con HepG2.
(Universidad Autónoma de Guerrero (México), 2020-01)
Insulin resistance (RI) is defined as the inability of insulin to internalize glucose in its target cells, favoring the development of metabolic diseases. The liver plays an important role in the development of RI; hence, ...
Efecto de la metformina sobre marcadores bioquímicosmoleculares y secreción de exosomas en células HUH7 con resistencia a insulina.
(Universidad Autónoma de Guerrero (México), 2020-01)
Liver-specific insulin resistance is associated with the development of the main challenges in metabolism resulting in dyslipidemia, hyperinsulinemia and hyperglycemia. In vitro models developed for researching the hepatic ...
Identificación de alteraciones en las lipoproteínas HDL y LDL en personas con resistencia a la insulina.
(Universidad Autónoma de Guerrero (México), 2021-01)
Background: Insulin resistance (IR) is a pathophysiological state in which there is a reduced capacity of insulin-sensitive tissues to respond to the action of this hormone. IR plays an important role in the alteration of ...
Efecto de la sobreexpresión de miR-411-5p sobre el nivel de GRB2, la proliferación y migración en células AGS.
(Universidad Autónoma de Guerrero (México), 2021-07)
Background: Dysregulation of microRNAs is associated with multiple human diseases, including cancer. Multiple studies have demonstrated the alteration of miR-411-5p and its duality of function in human cancer. Particularly ...
Actividad antiproliferativa y antimigratoria de extractos orgánicos de Tagetes en líneas celulares de cáncer cervicouterino.
(Universidad Autónoma de Guerrero (México), 2021-02)
Background Tagetes species are widely used in traditional medicine and have been shown to exert diverse biological activities due to its phytochemical constituents, including those related to cancer. Objetives: The present ...
Red de regulación hsa_circ_0009910/miR-198/c-MET: posible papel en la carcinogénesis cervical.
(Universidad Autónoma de Guerrero (México), 2021-06)
Background: Circular RNAs (circRNAs) are a type of non-coding RNA recently identified as regulators of tumorigenesis due they are efficient competing endogenous RNAs (ceRNAs) and regulate important processes such as ...
Caracterización in silico y molecular del LncRNA MINCR y su posible papel en la migración en células C33-A/AA-c de E6 del VPH-16.
(Universidad Autónoma de Guerrero (México), 2021-12)
Infection with human papillomavirus 16 (HPV-16) is one of the first events in the carcinogenesis process in cervical cancer (CC). The expression of the viral oncoprotein E6 and E7 is essential in this process to inactivate ...
Resistencia a la insulina cerebral y su relación con la resistencia a la insulina periférica en un modelo in vivo de obesidad.
(Universidad Autónoma de Guerrero (México), 2021-06)
Introduction: Insulin resistance (IR) is a condition that characterizes metabolic disorders, such as obesity and type 2 diabetes mellitus, which causes insulin-dependent tissues to alter their metabolism due to lack of ...
Análisis de la interacción de E6-prototipo de VPH-16 y sus variantes E6-AAa y E6-AAc con MAGI 1 y el efecto en su degradación.
(Universidad Autónoma de Guerrero (México), 2021-11-05)
Oncogenic protein E6 from Human Papilloma Virus 16 (HPV-16) 18 mediates the degradation of Membrane-associated guanylate kinase with inverted 19 domain structure-1 (MAGI-1), throughout the interaction of its protein binding ...
Efecto de la expresión de la oncoproteína E6 de las variantes AA-a, E-G350 y E-A176/G350 del VPH-16 en la metilación de genes relacionados con adhesión, migración e invasión celular.
(Universidad Autónoma de Guerrero (México), 2021-07)
Several studies have shown that DNA hypermethylation is one of the main alterations that occur with greater frequency in the establishment of cervical carcinoma. The VPH E6 oncoprotein has already been shown to promote the ...