• Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects 

      Dominguez Reyes, Teresa; Astudillo Lopez, Constanza Cecilia; Guzman Guzman, Iris Paola; Salgado Goytia, Lorenzo; Castro Alarcon, Natividad; Moreno Godinez, Ma. Elena; Muñoz Valle, Jose Francisco; Parra Rojas, Isela; Salgado Bernabé, Aralia B (BioMed Central, 2015-09-13)
      Background: Diet is an important environmental factor that interacts with genes to modulate the likelihood of developing disorders in lipid metabolism and the relationship between diet and genes in the presence of other ...
    • Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells 

      Villanueva Duque, José Alfredo; Zúñiga Eulogio, Miriam Daniela; Dena Beltran, José Luis; Castañeda Saucedo, Eduardo; Calixto Galvez, Mercedes; Mendoza Catalán, Miguel Ángel; Ortuño Pineda, Carlos; Navarro Tito, Napoleon (Clin Exp Pathol, 2017-10-15)
      Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression ...
    • Macrophage migration inhibitory factor promoter polymorphisms (-794 CATT5 and -173 G>C): relationship with mRNA expression and soluble MIF levels in young obese subjects 

      Matia García, Inés; Salgado Goytia, Lorenzo; García Arellano, Samuel; Parra Rojas, Isela (Hindawi Publishing Corporation, 2015-03-30)
      We analyzed the relationship of -794 CATT5 and -173 G>C MIF polymorphisms with mRNA and soluble MIF in young obese. A total of 250 young subjects, 150 normal-weight and 100 obese subjects, were recruited in the study. ...
    • Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions 

      Torres Rojas, Francisco Israel; Alarcón Romero, Luz Del Carmen; Leyva Vazquez, Marco Antonio; Ortiz Ortiz, Julio; Mendoza Catalán, Miguel Ángel; Hernández Sotelo, Daniel; Del Moral Hernández, Oscar; Rodríguez Ruiz, Hugo Alberto; Leyva Illades, Dinorah; Flores Alfaro, Eugenia; Illades_Aguiar, Berenice (Oncology Letters, 2017-09-13)
      High-risk human papillomavirus (HPV) is the primary cause of cervical carcinoma (CC). Viral integration into the host chromosomes is associated with neoplastic progression, and epigenetic changes may occur as a result. The ...
    • MicroRNA miR-16-1 regulates CCNE1 (cyclin E1) gene expression in human cervical cancer cells 

      Zubillaga Guerrero, Ma. Isabel; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Flores Alfaro, Eugenia; Peralta Zaragoza, Oscar (International Journal of Clinical and Experimental Medicine, 2015-09-30)
      MicroRNAs are involved in diverse biological processes through regulation of gene expression. The microRNA profile has been shown to be altered in cervical cancer (CC). MiR-16-1 belongs to the miR-16 cluster and has been ...
    • miR-23b as a potential tumor suppressor and its regulation by DNA methylation in cervical cancer 

      Campos Viguri, Gabriela Elizabeth; Jiménez Wences, Hilda; Torres Altamirano, Gricenda; Hernández Sotelo, Daniel; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Fernandez Tilapa, Gloria (Infectious Agents and Cancer, 2015-01)
      The aberrant expression of miR-23b is involved in the development and progression of cancer. The aim of this study was to evaluate the potential role of methylation in the silencing of miR-23b in cervical cancer celllines ...
    • Nuclear expression of Rac1 in cervical premalignant lesions and cervical cáncer cells 

      Mendoza Catalán, Miguel Ángel; Cristóbal Mondragón, Gema Rosa; Del Valle Flores, Heidi Nayeli; Romero Hernández, Mirna Azalea; Alarcón Romero, Luz Del Carmen; Illades_Aguiar, Berenice; Castañeda Saucedo, Eduardo (BMC Cancer, 2012-03-23)
      Abnormal expression of Rho-GTPases has been reported in several human cancers. However, the expression of these proteins in cervical cancer has been poorly investigated. In this study we analyzed the expression of the ...
    • Polymorphisms in the LPL and CETP genes and haplotype in the ESR1 gene are associated with metabolic syndrome in women from Southwestern México 

      Cahua Pablo, Jose Angel; Méndez Palacios, Abigael; Antúnez Ortiz, Diana Lizzete; Vences Velázquez, Amalia; Alarcón Romero, Luz Del Carmen; Tello Flores, Vianet Argelia; Leyva Vazquez, Marco Antonio; Pérez Macedonio, Claudia Paola; Flores Alfaro, Eugenia (International Journal of Molecular Sciences, 2015-09-08)
      Metabolic syndrome (MetS) is a combination of metabolic disorders associated with an increased risk for cardiovascular disease (CVD). Studies in women reported associations between polymorphisms in ESR1, LPL and CETP genes ...
    • Relevance of miR-21 in regulation of tumor suppressor gene PTEN in human cervical cancer cells 

      Peralta Zaragoza, Oscar; Deas, Jessica; Meneses Acosta, Angelica; De La O Gomez, Faustino; Fernandez Tilapa, Gloria; Gomez Ceron, Claudia; Benitez Boijseauneau, Odelia; Burguete Garcia, Ana Isabel; Torres Poveda, Kirvis Janneth; Bermúdez Morales, Victor Hugo; Madrid Marina, Vicente; Rodriguez Dorantes, Mauricio; Hidalgo Miranda, Alfredo; Perez Plasencia, Carlos Guadalupe (BioMed Central, 2016-03-14)
      Background: Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins ...
    • Risk of progression of early cervical lesions is associated with Integration and persistence of HPV-16 and expression of E6, Ki-67, and telomerase) 

      Vega Peña, Arianna; Illades_Aguiar, Berenice; Flores Alfaro, Eugenia; Leyva Vazquez, Marco Antonio; Castañeda Saucedo, Eduardo; Alarcón Romero, Luz Del Carmen (2015-09-04)
      Low-grade squamous intraepithelial lesions (LSIL) are the earliest lesions of the uterine cervix, the persistence and integration of high-risk human papillomavirus (HR-HPV) as type 16, which promotes the development of ...
    • The effects of heat activation on bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins 

      Cruz Mora, José (Applied and Environmental Microbiology, 2015-02-13)
      Nutrient germination of spores of Bacillus species occurs through germinant receptors (GRs) in spores'inner membrane (IM) in a process stimulated by sublethal heat activation. Bacillus subtilis spores maximum germination ...
    • The gerW protein Is not involved in the germination of spores of bacillus species 

      Cruz Mora, José (PLoS ONE, 2015-03-19)
      Germination of dormant spores of Bacillus species is initiated when nutrient germinants bind to germinant receptors in spores' inner membrane and this interaction triggers the reléase of dipicolinic acid and cations from ...
    • Tumor suppressor miR-29c regulates radioresistance in lung cancer cells 

      Aréchaga Ocampo, Elena; Lopez Camarillo, Mario Cesar; Villegas Sepulveda, Nicolas; Gonzalez De La Rosa, Claudia Haydee; Perez Añorve, Isidro Xavier; Roldan Perez, Reynalda; Flores Perez, Jose Ali; Peña Curiel, Omar; Angeles Zaragoza, Oscar; Rangel Corona, Rosalva; Gonzalez Barrios, Juan Antonio; Bonilla Moreno, Raúl; Del Moral Hernandez, Oscar; Herrera, Luis A; Garcia Carranca, Alejandro Manuel (Tumor Biology, 2017-03)
      Radiotherapy is an important treatment option for non-small cell lung carcinoma patients. Despite the appropriate use of radiotherapy, radioresistance is a biological behavior of cancer cells that limits the efficacy of ...
    • Variaciones de número de copias: marcadores y predictores de diabetes tipo 2 

      Antúnez Ortiz, Diana Lizzete; Flores Alfaro, Eugenia (Revista Medica Instituto Mexicano Seguro Social, 2014-07-15)
      Type 2 diabetes (T2D) is a disease characterized by a defi ciency in production or action of insulin. It is the result mainly of the interaction of the environment, lifestyle, as well as genetic factors. It is considered ...